Sulfamethoxazole Bulk Supply for Industrial Use

China Factory Direct
CAS number 723-46-6
Product name Sulfamethoxazole
Stock Stock readily available; annual supply capacity exceeding 1,000 tons.
Grade Reagent Grade
Packaging 25KG/bag500KG/bag1000KG/bag
Sample Test Samples Available (Click to Request Samples)
COA View COA
Price Get Quote
Supply Type Bulk / Contract manufacturing / OEM
Shipping FCL / LCL available
Payment Terms Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
Manufacturer Greenrock Chemical(China Factory)
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EXW (Ex Works)

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CAS No:723-46-6
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Documents We Provide for Sulfamethoxazole

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart
Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Sulfamethoxazole Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of Sulfamethoxazole

Industry Application Process
Pharmaceuticals Antibacterial agent Acts by inhibiting a key enzyme in bacterial folate synthesis, thereby preventing bacterial growth and replication. Sulfamethoxazole is typically administered orally as tablets or capsules, or intravenously as an injection.
Veterinary Antibacterial treatment for animals Applied in the treatment of infectious diseases in poultry, swine, and other livestock. Formulated into animal-appropriate dosage forms, such as soluble powders for drinking water or premixes.
Research Laboratory research Used as a positive control substance in antimicrobial activity assays; or employed in microbiological studies to investigate its mechanism of action.

Manufacturing Quality Control of Sulfamethoxazole

Test Item Commonly Used Testing Method Method Overview
Content Determination High-Performance Liquid Chromatography (HPLC) A C18 column is used, with methanol-water or a buffer (e.g., phosphate buffer) as the mobile phase. Detection is performed at 254 nm using a UV detector. Quantification is done by external or internal standard method. It offers high accuracy and good reproducibility, and is the pharmacopoeia-recognized method.
Ultraviolet Spectrophotometry (UV) Measures absorbance at 254 nm. Suitable for preliminary content determination of pure substances or formulations. Simple to operate but susceptible to interference from impurities; purity testing should be conducted as a supplement.
Impurity Testing High-Performance Liquid Chromatography (HPLC) Uses gradient or isocratic elution to detect related substances (e.g., sulfonamide impurities, degradation products, synthesis intermediates). Impurity content is calculated by comparison with reference standards, meeting the limit requirements specified in the Chinese Pharmacopoeia.
Dissolution (for formulations) UV-Visible Spectrophotometry / HPLC According to pharmacopoeial specifications for dissolution medium (e.g., pH 6.8 phosphate buffer) and rotation speed, samples are taken at specified time intervals. The release amount is measured by UV or HPLC to evaluate the bioavailability of the formulation.
Related Substances (Impurity Profile) HPLC-Mass Spectrometry (HPLC-MS) Based on HPLC separation, unknown impurities are identified by mass spectrometry. Suitable for impurity analysis during the development phase or in complex samples. Offers high sensitivity with both qualitative and quantitative capabilities.
Moisture Determination Karl Fischer Titration Utilizes the quantitative reaction of iodine-sulfur dioxide-pyridine-methanol system with water to accurately determine trace moisture in active pharmaceutical ingredients (APIs). Complies with pharmacopoeial standards and is considered the gold standard for moisture control.
Residual Solvents Gas Chromatography (GC) Uses a capillary column and FID detector to analyze residual organic solvents (e.g., ethanol, acetone, dichloromethane) that may remain after manufacturing. Limits are controlled according to ICH Q3C guidelines.
Heavy Metals Atomic Absorption Spectroscopy (AAS) or ICP-MS After ashing or digesting the sample, heavy metals such as lead, arsenic, cadmium, and mercury are measured by AAS or inductively coupled plasma mass spectrometry (ICP-MS), meeting pharmacopoeial limits (e.g., ≤20 ppm).
Particle Size Distribution (for APIs) Laser Diffraction / Microscopy Used to control the particle size of API powders, which affects dissolution rate and dosage uniformity. Particularly important for controlling raw materials in poorly soluble formulations.
Crystal Form Analysis X-Ray Powder Diffraction (XRPD) Identifies the crystal form of sulfamethoxazole (e.g., anhydrate, hydrate) based on characteristic diffraction peaks. Ensures consistency in crystal form to prevent changes in stability and dissolution performance.
pH Value (solution) Glass Electrode Method (pH Meter) A solution of specified concentration is prepared, and its pH is measured using a calibrated pH meter to ensure the acidity or alkalinity of the formulation or injection meets the specified range (usually pH 5.0–7.5).
Heavy Metal Ions (e.g., Iron Salts) Thiocyanate Colorimetry In acidic conditions, iron reacts with thiocyanate to form a red complex, which is quantified by colorimetry. Suitable for the control of specific metal ions as specified in the pharmacopoeia.

Technical Specifications of Sulfamethoxazole

Test Item Specification
Appearance White crystalline solid
Purity >=98.0% (HPLC)
Water Content (KF) <=0.5%
Melting Point 168–172°C
Total Impurities <=2.0%
Single Impurity <=0.5%
Residue on Ignition <=0.1%
Heavy Metals <=20 ppm
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of Sulfamethoxazole

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NMR Spectra of Sulfamethoxazole

Safety Information of Sulfamethoxazole

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Safety Data Sheet

Packaging of Sulfamethoxazole

We have a diverse range of chemicals in stock. Available in Bagged goods (25 kg.),Big bags (500 kg.), Big bags (1000 kg.).

Industrial Sulfamethoxazole Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

Industrial
Use
Bulk
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Factory
Direct
ISO 9001
Certified
Samples
Available
Stable
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