China Factory Direct
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| CAS number | 7250-53-5 |
| Product name | Quinoline-5-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), including antimalarial agents, antimicrobial agents, and kinase inhibitors | Constructs the target molecular scaffold via organic synthesis reactions such as amidation, esterification, or Suzuki cross-coupling |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of heterocyclic compounds with insecticidal or fungicidal activity | Introduces the quinoline carboxylic acid structural motif via nucleophilic substitution, cyclization, or transition-metal-catalyzed cross-coupling reactions |
| Materials Science | Used as a ligand in the preparation of metal–organic frameworks (MOFs) or coordination polymers | Coordinates with transition metal ions (e.g., Zn²⁺, Cu²⁺) to form porous crystalline materials through self-assembly |
| Analytical Chemistry | Serves as a structural scaffold for fluorescent probes or metal ion recognition reagents | Introduces recognition moieties via modification of carboxyl groups or nitrogen atoms for selective detection of specific metal ions (e.g., Al³⁺, Zn²⁺) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies quinoline-5-carboxylic acid concentration by UV absorption at 254 nm using a reversed-phase C18 column and external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities (e.g., isomers, decarboxylated or oxidized derivatives) via gradient elution and peak area comparison. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., methanol, toluene, DMF) using flame ionization detection after headspace or direct injection. |
| Heavy Metals | ICP-OES | Determines total elemental metal content (Pb, Cd, Hg, As, Cr) by plasma excitation and atomic emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column and conductivity detection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration with iodine generated electrochemically in pyridine/methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity against defined reference standards under controlled lighting conditions. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using angular scattering intensity of laser light. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.