China Factory Direct
|
|
| CAS number | 7251-52-7 |
| Product name | Phenyl-(2-pyridyl)acetamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing antitumor or anti-inflammatory active compounds | Organic synthesis reactions, including amide coupling and cyclization |
| Chemical Research | Building block for ligands or functional molecules containing pyridyl and phenyl motifs | Modular synthesis in coordination chemistry or molecular design |
| Agrochemical R&D | Potential lead compound for developing novel insecticidal or fungicidal agents | Process integrating structural modification with biological activity screening |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual Inspection + Physical Property Measurement | Observe sample color and physical state (white or off-white crystalline powder), determine melting point range (literature value approximately 120–125 °C), and evaluate flowability and hygroscopicity. |
| Content Determination (Main Component Purity) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with methanol-water (or buffer) as the mobile phase, UV detector (254 nm or 280 nm), external standard method for quantification. Calculate the area percentage of the main peak; typically required ≥98.0%. |
| Related Substances (Impurity Profile) | HPLC Method (Gradient Elution) | Use gradient elution to separate degradation products, starting material residues, and synthetic intermediates. Detect at 254 nm; calculate the percentage of each impurity peak area relative to total peak area, complying with ICH Q3B limits. |
| Solvent Residues | Gas Chromatography (GC) | Use headspace injection or direct injection with DB-624 or HP-INNOWAX columns and FID detector. Detect residual solvents such as ethanol, acetone, ethyl acetate, conforming to ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration | Determine trace moisture using coulometric or volumetric Karl Fischer method. Control moisture content ≤0.5% (based on formulation requirements) to prevent hydrolysis or stability issues. |
| Melting Point | Melting Point Apparatus Measurement | Determine using capillary method or automated melting point instrument. Compare with literature values (~120–125 °C) to assess crystal form consistency and purity. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Dissolve sample in ethanol or methanol, measure absorption spectrum from 200–400 nm. Characteristic absorption peaks around 250 nm and 280 nm for qualitative confirmation and concentration estimation. |
| Chloride/Heavy Metals | General Chapters of Chinese Pharmacopoeia Methods | Chloride tested by silver nitrate colorimetry; heavy metals analyzed by thioacetamide method (suitable for inorganic impurity control). Ensure compliance with pharmaceutical-grade standards (e.g., ≤10 ppm). |
| Particle Size Distribution (if applicable) | Laser Diffraction or Microscopy | If used as a raw material for powder formulations, determine D50 particle size to ensure dissolution performance and process consistency. Typically controlled within 10–50 μm. |
| Polymorphic Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | Used to confirm crystalline form, avoiding polymorphism that may affect solubility and bioavailability. Compare with reference pattern to confirm consistency. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 148–152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Identification (NMR) | Consistent with structure |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.