1-Isobutyl-4-piperidone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 72544-16-2 |
| Product name | 1-Isobutyl-4-piperidone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Isobutyl-4-piperidone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Isobutyl-4-piperidone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Isobutyl-4-piperidone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of opioid analgesics (e.g., oxycodone, oxymorphone) | Condensed with aldehydes in reductive amination, followed by catalytic hydrogenation or sodium borohydride reduction to yield target drug molecules |
| Pharmaceuticals | Structural building block for selective 5-HT2C receptor agonists (e.g., lorcaserin) | Serves as a piperidine ring precursor in multistep coupling and functional group transformations to construct the N-isobutylpiperidine scaffold |
| Agrochemicals | Intermediate in the development of novel insecticides and plant growth regulators | Introduces an N-alkylpiperidine moiety with balanced steric bulk to optimize binding affinity toward target enzymes (e.g., acetylcholinesterase) |
| Materials Science | Functional monomer for high-performance polymers (e.g., polyamides, polyurethanes) | Introduces rigid hydrophobic groups via the N-alkylpiperidine ring to enhance polymer thermal stability and mechanical properties |
Manufacturing Quality Control of 1-Isobutyl-4-piperidone
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color, physical state (e.g., colorless to pale yellow liquid or crystals), clarity, and presence of particulates or impurities. |
| Assay | Gas Chromatography (GC) | Separation using a capillary column, with FID detection; quantification of the main component by internal or external standard method to evaluate purity. |
| High-Performance Liquid Chromatography (HPLC) | Suitable for thermally unstable or non-volatile samples; uses C18 column with UV detection (e.g., 210–220 nm), and external standard method for quantification. | |
| Related Substances / Impurity Analysis | GC or HPLC (Gradient Elution) | Identification and quantification of impurities such as by-products, residual starting materials, and degradation products by comparing retention times with the main peak. |
| Water Content | Karl Fischer Titration | Determines trace moisture content using volumetric or coulometric method to ensure compliance with drying requirements. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Qualitative and quantitative analysis of organic solvents potentially remaining from the manufacturing process (e.g., toluene, ethanol, ethyl acetate). |
| Melting Point (if solid) | Capillary Melting Point Method | Determines the melting temperature range of solid samples to assess purity and crystalline form consistency. |
| pH Value (in solution) | pH Meter Method | Sample is dissolved in water or a suitable solvent at a defined concentration; pH is measured to evaluate stability or the influence of salt form. |
| Density / Refractive Index | Densitometer / Abbe Refractometer | Measures auxiliary physical constants for batch-to-batch consistency comparison and preliminary identification. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹³C-NMR are used to confirm characteristic peaks of molecular structure and verify the correctness of the target compound. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Compares characteristic functional group absorption peaks (e.g., carbonyl C=O ~1700 cm⁻¹) to assist in structural identification. | |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Controls heavy metals (e.g., Pd, Ni, Cu) introduced from catalysts or manufacturing processes to ensure compliance with pharmacopoeial or customer-specified limits. |
Technical Specifications of 1-Isobutyl-4-piperidone
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Isobutyl-4-piperidone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 1-Isobutyl-4-piperidone
Industrial 1-Isobutyl-4-piperidone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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