2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 72587-18-9 |
| Product name | 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for novel insecticides, used in synthesizing neonicotinoid insecticides such as sulfoxaflor | Prepared via cyclization and substitution reactions with sodium thiosulfate, ethyl chloroformate, and other reagents to yield the target insecticidal active ingredient |
| Pharmaceuticals | Structural modification intermediate in anticancer and antiviral drug development | Used to construct kinase inhibitors containing a trifluoromethylpyridine scaffold, e.g., by introducing pharmacophores via Suzuki coupling or reductive amination |
| Materials Science | Functional unit in organic optoelectronic materials, used to synthesize high-electron-affinity n-type semiconductor small molecules | Employed as an electron-accepting unit in Stille or Suzuki cross-coupling reactions with donor units (e.g., thiophene derivatives) to build conjugated polymers or small-molecule materials |
Manufacturing Quality Control of 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV/DAD | Separation and identification of structurally related impurities (e.g., regioisomers, dehalogenated or hydrolyzed by-products) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Quantification of residual solvents (e.g., methanol, dichloromethane, toluene) via headspace GC with flame ionization detection, per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni, As) after acid digestion, achieving sub-ppt detection limits per ICH Q3D. |
| Chloride Content | Ion Chromatography (IC) | Separation and quantification of chloride ion (from potential hydrolysis or salt impurities) using suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-state phase transition temperature using calibrated digital apparatus, indicating crystallinity and purity. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Measurement of non-volatile inorganic residue after high-temperature incineration (~750 °C) followed by weighing. |
| Optical Rotation | Polarimetry | Assessment of chiral purity (if applicable) via measurement of specific rotation in solution using sodium D-line light. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values, relevant for handling and formulation performance. |
Technical Specifications of 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
Safety Information of 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE
Industrial 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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