China Factory Direct
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| CAS number | 72594-77-5 |
| Product name | BOC-L-TYROSINE ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for peptide synthesis | Used as a protected amino acid to incorporate tyrosine residues in solid-phase or solution-phase peptide synthesis; the amino group is protected by tert-butoxycarbonyl (Boc), and the carboxyl group is protected as an ethyl ester |
| Biochemistry | Synthesis of biologically active peptides | Applied in the preparation of hormones, enzyme inhibitors, or other pharmacologically active peptides via deprotection and coupling reactions into peptide chains |
| Organic Synthesis | Building block for constructing complex molecular structures | Employed as a chiral synthon in organic synthetic routes, participating in amide bond formation reactions for total synthesis of natural products |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 220 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., ethyl acetate, toluene, methanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent where water reacts stoichiometrically to determine trace moisture content. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantitative determination of toxic elements (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residual Palladium | ICP-OES | Post-digestion analysis by inductively coupled plasma optical emission spectrometry to detect residual Pd from catalytic hydrogenation steps. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under specified vacuum/temperature conditions to assess volatile and moisture content. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to calculate particle size distribution in dry powder form. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | +1.5 to +2.5° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.