2-Chloromethyl-3,4-dimethoxypyridinium chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 72830-09-2 |
| Product name | 2-Chloromethyl-3,4-dimethoxypyridinium chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloromethyl-3,4-dimethoxypyridinium chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloromethyl-3,4-dimethoxypyridinium chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloromethyl-3,4-dimethoxypyridinium chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Manufacturing | Key intermediate for proton pump inhibitors (e.g., omeprazole, lansoprazole) | Condensed with benzimidazole derivatives under basic conditions, followed by oxidation to produce the target drug |
| Pharmaceutical R&D | Structural modification agent for novel proton pump inhibitors and anti-ulcer agents | Used to construct the pyridylmethylbenzimidazole scaffold to optimize pharmacokinetic properties |
Manufacturing Quality Control of 2-Chloromethyl-3,4-dimethoxypyridinium chloride
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical form (e.g., white or off-white crystalline powder), and presence of foreign particles or caking. |
| Identification | Infrared Spectroscopy (IR) | Compare the infrared absorption spectrum with a reference spectrum to confirm characteristic functional groups and verify the compound's identity. |
| Identification | High-Performance Liquid Chromatography (HPLC) | Compare retention time with that of a reference standard under identical chromatographic conditions to confirm consistency of the active ingredient. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Quantify the main component using external standard method or area normalization method; typically requires ≥98.0% or compliance with internal company specifications. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main peak from impurity peaks using gradient or isocratic elution; calculate individual impurity levels by area normalization or self-dilution method. |
| Loss on Drying | Oven Drying Method (105°C to constant weight) | Weigh sample, dry in an oven at 105°C until constant weight, then calculate percentage weight loss to control moisture and volatile content. |
| Sulfated Ash / Residue on Ignition | High-Temperature Ashing Method (600–800°C) | Ignite sample at high temperature and weigh the residual inorganic matter to assess inorganic impurities or metal catalyst residues. |
| Heavy Metals | Heavy Metals Test as per Chinese Pharmacopoeia (Thioacetamide Method) | React with thioacetamide under weakly acidic conditions to produce color; compare with a lead standard solution to limit total heavy metals (e.g., ≤20 ppm). |
| Chloride Content | Argentometric Method (Volhard Method or Potentiometric Titration) | Titrate free chloride ions with silver nitrate; determine endpoint via precipitation or potentiometric titration to verify salt formation ratio in hydrochloride salts. |
| pH Value (Aqueous Solution) | pH Meter Measurement | Prepare a solution of specified concentration and measure pH using a calibrated pH meter to evaluate acidity/alkalinity for process or stability requirements. |
| Residual Solvents | Gas Chromatography (GC, Headspace Injection) | Detect organic solvents potentially remaining from synthesis (e.g., methanol, dichloromethane, ethyl acetate) according to ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range; used as a physical constant to assist in identification and purity assessment (if applicable). |
Technical Specifications of 2-Chloromethyl-3,4-dimethoxypyridinium chloride
| Test Item | Specification |
|---|---|
| Appearance | White to orange to green crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168–172°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.3% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloromethyl-3,4-dimethoxypyridinium chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloromethyl-3,4-dimethoxypyridinium chloride
Safety Information of 2-Chloromethyl-3,4-dimethoxypyridinium chloride
| Pictograms |    |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloromethyl-3,4-dimethoxypyridinium chloride
Industrial 2-Chloromethyl-3,4-dimethoxypyridinium chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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