(R)-1-N-Boc-beta-proline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 72925-16-7 |
| Product name | (R)-1-N-Boc-beta-proline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-N-Boc-beta-proline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-N-Boc-beta-proline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-N-Boc-beta-proline
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used to synthesize biologically active pyrrolidine-based drug molecules; serves as a chiral building block in coupling reactions |
| Pharmaceutical R&D | Chiral auxiliary | Provides (R)-configuration in asymmetric synthesis to control product stereochemistry |
| Fine chemicals | Boc protecting group introduction | Introduces the tert-butoxycarbonyl (Boc) group to protect amines, enhancing reaction selectivity and stability |
| Pharmaceutical manufacturing | Peptide and peptidomimetic compound synthesis | Serves as a structural unit to construct nitrogen-containing heterocyclic scaffolds for drug development, including protease inhibitors |
Manufacturing Quality Control of (R)-1-N-Boc-beta-proline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification via UV absorbance at characteristic wavelength using a calibrated reference standard and reverse-phase column. |
| Chiral Purity | Chiral HPLC | Enantiomeric separation on a chiral stationary phase with UV detection; peak area ratio determines (R)-enantiomer excess. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in anhydrous methanol-based medium. |
| Residual Solvents | GC-FID | Separation and quantification of volatile solvents by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion by measuring atomic emission intensities in plasma. |
| Chloride Impurity | Ion Chromatography | Separation of anions on ion-exchange column with conductivity detection; chloride identified by retention time and response. |
| Sulfate Impurity | Ion Chromatography | Same principle as chloride; sulfate quantified based on retention time and calibrated conductivity signal. |
| Residual Boc Reagent | GC-MS | Detection and quantification of di-tert-butyl dicarbonate by gas chromatography coupled with mass spectrometric identification. |
| Related Substances | HPLC-UV | Detection of structurally related impurities using gradient reverse-phase HPLC with UV monitoring at multiple wavelengths. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under specified temperature and vacuum conditions to determine volatile content. |
Technical Specifications of (R)-1-N-Boc-beta-proline
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -16.0 to -14.0 deg (c=1, in CHCl3) |
| Melting Point | 78.0 to 82.0 °C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-N-Boc-beta-proline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-N-Boc-beta-proline
Packaging of (R)-1-N-Boc-beta-proline
Industrial (R)-1-N-Boc-beta-proline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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