3-Bromothiophene-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7311-64-0 |
| Product name | 3-Bromothiophene-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Bromothiophene-2-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Bromothiophene-2-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Bromothiophene-2-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate in new drug development | Used to synthesize thienyl-based pharmaceutical molecules, such as the nonsteroidal anti-inflammatory drug tiaprofenic acid and its derivatives |
| Agrochemicals | Intermediate for fungicide and insecticide synthesis | Applied in constructing thienyl-based agrochemical active ingredients via amidation, esterification, or Suzuki coupling reactions |
| Organic Synthesis | Building block for 2,3-disubstituted thiophene derivatives | Leverages reactivity of the carboxyl group and bromine atom for decarboxylative coupling or intramolecular cyclization reactions |
| Materials Science | Monomer for organic optoelectronic materials | Serves as an electron-accepting or functionalized monomeric unit in condensation polymerization to produce organic semiconductor materials |
Manufacturing Quality Control of 3-Bromothiophene-2-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of impurities (e.g., 3-bromothiophene, 2-carboxythiophene, brominated dimers) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection or mass spectrometry to quantify residual solvents (e.g., DMF, THF, methanol) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS or ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni) after acid digestion, based on USP <232>/<233> limits. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions (e.g., from incomplete bromination or hydrolysis) using suppressed conductivity detection or argentometric titration. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic ash content after high-temperature incineration at 700–800 °C per USP <281>. |
Technical Specifications of 3-Bromothiophene-2-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 75–79 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Bromothiophene-2-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Bromothiophene-2-carboxylic acid
Safety Information of 3-Bromothiophene-2-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Bromothiophene-2-carboxylic acid
Industrial 3-Bromothiophene-2-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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