2-Bromo-5-iodopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 73290-22-9 |
| Product name | 2-Bromo-5-iodopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-5-iodopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-5-iodopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-5-iodopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Used as an aryl halide in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct C–C bonds |
| Pesticide Development | Used in the design and synthesis of novel nitrogen-containing heterocyclic insecticides and fungicides | Enables introduction of specific substituents via halogen exchange or coupling reactions to optimize molecular bioactivity |
| Organic Synthesis | Multifunctional heterocyclic building block for constructing complex pyridine derivatives | Applied as a dihalogenated substrate for selective monohalogen functionalization (e.g., selective iodination or bromination) or participation in multistep cascade reactions |
Manufacturing Quality Control of 2-Bromo-5-iodopyridine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity | High-Performance Liquid Chromatography (HPLC) | Reverse-phase C18 column is used with methanol/water or acetonitrile/water as the mobile phase, and UV detection (e.g., 254 nm) is employed to quantify the main peak area for purity calculation. Suitable for separation and analysis of organic impurities from the main component. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR are used to analyze chemical shifts of hydrogen and carbon atoms, confirming whether the molecular structure matches the characteristic peaks of 2-bromo-5-iodopyridine. |
| Elemental Composition Verification | Elemental Analysis (EA) | Determines the content of C, H, and N elements in the sample and compares them with theoretical values (C₅H₃BrIN: C 23.60%, H 1.19%, N 5.50%) to verify the chemical composition. |
| Residual Impurities (Solvents) | Gas Chromatography (GC) | Headspace or direct injection using capillary columns, with FID or ECD detectors to quantitatively determine residual organic solvents (e.g., methanol, ethyl acetate). |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After microwave digestion, the concentrations of heavy metals such as As, Pb, Cd, and Hg are measured to ensure compliance with pharmacopoeial or customer-specified limits. |
| Melting Point | Digital Melting Point Apparatus | Measured via capillary method with gradual heating; initial and final melting temperatures are recorded and compared with literature values (~85–88°C) to assess crystalline purity. |
| Moisture Content | Karl Fischer Titration | Using coulometric or volumetric KF titrators to precisely measure trace moisture levels, ensuring the raw material meets required dryness specifications. |
| Residual Halogens (Br/I Ratio) | X-ray Fluorescence (XRF) or Titration Method | XRF provides non-destructive, rapid determination of Br/I elemental ratios; alternatively, after oxygen bottle combustion, silver nitrate titration is used to separately quantify bromine and iodine contents, verifying correct substitution positions. |
| Chiral Impurities (if applicable) | Chiral HPLC | If there is a potential chiral center risk (unlikely for this compound), chiral columns can be used to separate enantiomers and assess optical purity. |
Technical Specifications of 2-Bromo-5-iodopyridine
| Test Item | Specification |
|---|---|
| Appearance | Off White to Yellow Color powder |
| Purity | ≥98.0% |
| Water | ≤0.5% |
| Melting point | 120~123°C |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-5-iodopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-5-iodopyridine
Packaging of 2-Bromo-5-iodopyridine
Industrial 2-Bromo-5-iodopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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