5-BROMO-2,4-DIHYDROXYBENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7355-22-8 |
| Product name | 5-BROMO-2,4-DIHYDROXYBENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-BROMO-2,4-DIHYDROXYBENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing antifungal agents (e.g., terbinafine analogues) and antimicrobial compounds | Selective bromination at the 5-position of 2,4-dihydroxybenzoic acid, followed by recrystallization for purification |
| Agrochemical R&D | Structural building block for developing novel fungicides and plant growth regulators | Aromatic ring modification precursor used in coupling reactions (e.g., Suzuki or Ullmann reactions) to construct brominated heteroaromatic systems |
| Organic Synthesis | Multifunctional, functionalized aromatic building block for constructing complex natural products and functional molecules | Bromine atom participates in nucleophilic substitution and metal-catalyzed cross-coupling (Pd/Cu-catalyzed); hydroxyl group undergoes acylation, methylation, or protection/deprotection |
Manufacturing Quality Control of 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) based on retention time and calibration curves. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element determination after acid digestion; total heavy metals expressed as lead equivalent using plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anion on an anion-exchange column with conductivity detection, quantified against sodium chloride standard. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and weighing of residual inorganic ash. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content based on stoichiometric reaction. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid transforms to liquid. |
| Appearance | Visual Inspection | Assessment under controlled white light against defined criteria for color, clarity, and physical form (crystalline powder). |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a standardized suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Iron (Fe) Content | AAS | Atomic absorption spectroscopy after acid digestion and dilution; quantification using characteristic Fe absorption line at 248.3 nm. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured after drying at 105 C for 2 hours, reflecting volatile matter and residual solvents. |
Technical Specifications of 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 215–219 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
Safety Information of 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
Industrial 5-BROMO-2,4-DIHYDROXYBENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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