China Factory Direct
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| CAS number | 7356-11-8 |
| Product name | 4-Methyl-3-nitrobenzoic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of anticancer agents, antiviral agents, and other active pharmaceutical ingredients (APIs) | Used to construct the core molecular structure of target compounds via organic synthesis reactions including reduction, hydrolysis, acylation, or coupling |
| Agrochemicals | Intermediate in the synthesis of bioactive herbicides or insecticides | After nitro group reduction to amino, subjected to substitution or cyclization reactions to generate agrochemically active molecules |
| Dyes & Pigments | Precursor in the synthesis of azo dyes or functional dyes | The nitro or ester group participates in diazotization, coupling, or nucleophilic substitution reactions to introduce chromophores |
| Organic Synthesis | General aromatic building block for constructing complex aromatic compounds | Enables diverse molecular synthesis through functional group transformations—e.g., nitro-to-amino conversion or ester hydrolysis to carboxylic acid |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify methanol, ethyl acetate, and other process solvents against calibrated standards. |
| Moisture Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent where water reacts stoichiometrically, enabling precise quantification in non-aqueous matrix. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion and dilution; measures total content of Pb, Cd, Hg, As, and others against pharmacopeial limits. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on anion-exchange column with conductivity detection; quantified using external calibration. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 600 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change; reported as onset and clear point per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution; indicates chiral purity if applicable (though compound is achiral, used for consistency). |
| Appearance | Visual Inspection | Assessment of crystalline form, color, and absence of foreign particles under controlled white light against established reference standard. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension (e.g., 10 mg/mL) using calibrated electrode; reflects acidic impurity levels. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after ignition at 700 C; assesses non-volatile inorganic contaminants per USP <281>. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 75–79°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.