2-Chloro-4-bromopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 73583-37-6 |
| Product name | 2-Chloro-4-bromopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-bromopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-bromopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-bromopyridine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing broad-spectrum insecticides (e.g., chlorfenapyr) | Introduces the pyridine ring via nucleophilic substitution or coupling reactions to construct the ortho-aminobenzamide insecticide scaffold |
| Pharmaceuticals | Heterocyclic building block for synthesizing anticancer, anti-inflammatory, and kinase inhibitor drugs | Acts as a halogenated aromatic heterocycle in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct the core structure of bioactive molecules |
| Materials Science | Functionalized intermediate for organic light-emitting diodes (OLEDs) and organic semiconductor materials | Introduces electron-transporting/hole-blocking groups via metal-catalyzed C–N or C–C bond coupling to tune energy levels and charge-carrier mobility |
Manufacturing Quality Control of 2-Chloro-4-bromopyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities by retention time and UV absorbance relative to the main peak. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Volatile organic solvents are extracted into headspace gas and quantified via calibrated GC-FID or GC-MS. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water in the sample. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element detection of metallic impurities after acid digestion, based on element-specific emission wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column and quantification via conductivity response. |
| Bromide Impurity | Ion Chromatography (IC) with conductivity detection | Separation of bromide ions from matrix interferences and quantification using calibrated conductivity signal. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities (e.g., HBr, pyridinium salts) using phenolphthalein endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate; indicates crystallinity and purity. |
| Appearance | Visual Inspection against White Background | Assessment of physical state, color, and presence of visible particulates or discoloration in solid form. |
| Residue on Ignition | Gravimetric Analysis after High-Temperature Ashing | Non-volatile inorganic residue determined by weight difference before and after ignition at 700-800 C. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or degradation products in solution. |
Technical Specifications of 2-Chloro-4-bromopyridine
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 52.0–56.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-bromopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-bromopyridine
Packaging of 2-Chloro-4-bromopyridine
Industrial 2-Chloro-4-bromopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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