China Factory Direct
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| CAS number | 73724-45-5 |
| Product name | Fmoc-L-Serine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceutical R&D | Protective amino acid monomer for peptide synthesis | Used in solid-phase or solution-phase peptide synthesis; the Fmoc group protects the α-amino functionality, and the serine side-chain hydroxyl group is available for further modification or participation in reactions |
| Chemical reagent manufacturing | Synthetic intermediate | Serves as a building block for preparing complex peptides, protein mimetics, and functionalized biomolecules |
| Life sciences research | Synthesis of molecular probes and labeling agents | Integrated into the design and synthesis processes of modified peptides for fluorescent labeling, isotopic labeling, and other derivatization techniques |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer content determined by peak area ratio relative to total serine-related peaks. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent where water reacts stoichiometrically, enabling precise volumetric or coulometric quantification. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., DMF, DCM, MeOH) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues via atomic emission spectroscopy following microwave-assisted acid digestion. |
| Specific Optical Rotation | [alpha]D Measurement | Determination of chiral compound identity and purity by measuring the angle of rotation of plane-polarized light at 589 nm. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after controlled heating under vacuum or nitrogen, indicating volatile impurities and residual solvents. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-Ser-OH diastereomers, deprotected serine, diketopiperazine) using gradient RP-HPLC. |
| pH of Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in aqueous solution using calibrated glass electrode and pH meter. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting against established reference standards. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms by filtration, membrane transfer to culture medium, and colony counting after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -15.0 to -10.0 deg (c=1, in 1M HCl) |
| Melting Point | 175 to 179 °C |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.