China Factory Direct
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| CAS number | 73866-23-6 |
| Product name | 5-Bromoacetyl salicylamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key raw material for synthesizing salicylamide derivatives, applied in the preparation of drug molecules with anti-inflammatory and analgesic activities. |
| Pharmaceutical Chemicals | Chemical Reagent | Used in laboratory R&D to construct heterocyclic compounds via the reactivity of the bromoacetyl group (e.g., nucleophilic substitution reactions). |
| Organic Synthesis | Alkylating Agent | Introduces the acetylsalicylamide group into target molecules by leveraging the reactive bromine atom. |
| Test Item | Common Test Method | Method Summary |
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| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with a reference spectrum to confirm the presence of characteristic functional groups in 5-bromoacetyl salicylamide (such as amide, ester, aromatic ring, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze chemical shifts, integration areas, and coupling constants of hydrogen atoms in the molecule using NMR technology to verify whether the compound structure matches the expected structure of 5-bromoacetyl salicylamide. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase consisting of methanol-water or acetonitrile-water at an appropriate ratio. Detect using a UV detector (typically at 230–280 nm wavelength) and calculate the main component content by external standard or internal standard method. |
| Related Substances (Impurity Profiling) | High-Performance Liquid Chromatography (HPLC) | Employ gradient or isocratic elution to separate and detect potential impurities from synthesis processes (e.g., unreacted starting materials, by-products, degradation products), with limits controlled by area normalization or self-reference methods. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection, separate residual organic solvents (such as dichloromethane, methanol, ethanol, ethyl acetate, etc.) on a capillary column with FID detection. Ensure levels comply with ICH Q3C guidelines. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Loss on Drying at Atmospheric Pressure | Dry the sample to constant weight at a specified temperature (e.g., 105°C) and measure the percentage loss in mass due to moisture or other volatile components to evaluate the degree of dryness. |
| Melting Point | Capillary Melting Point Determination | Pack the sample into a capillary tube and gradually heat in a melting point apparatus; observe the initial and final melting temperatures to assess purity and crystalline form consistency. |
| Heavy Metals | Thioacetamide Method (Colorimetry) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | According to general chapters of the Chinese Pharmacopoeia, semi-quantitatively detect total heavy metals via color-forming reactions; for higher sensitivity requirements, use ICP-MS to accurately determine trace elements such as lead, cadmium, mercury, and arsenic. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 148°C - 152°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.