2',3',5'-Tri-O-acetyl-D-adenosine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7387-57-7 |
| Product name | 2',3',5'-Tri-O-acetyl-D-adenosine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2',3',5'-Tri-O-acetyl-D-adenosine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2',3',5'-Tri-O-acetyl-D-adenosine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2',3',5'-Tri-O-acetyl-D-adenosine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for Drug Synthesis | Serves as a key raw material for synthesizing adenosine and its derivatives (e.g., S-adenosylmethionine, adenosylcobalamin), leveraging the acetyl protecting groups on the sugar ring to enable selective chemical reactions. |
| Pharmaceutical Industry | Raw Material for Antiviral and Nucleic Acid-Based Drugs | Used in the synthesis of antiviral nucleoside analogues via deacetylation and glycosylation modifications to produce the target drug molecules. |
| Biochemistry/Research | Synthesis of Biochemical Reagents and Labels | Serves as a precursor for enzyme substrates or labeling agents, enabling synthesis of fluorescently or biotin-labeled adenosine derivatives commonly applied in affinity chromatography or signal detection. |
| Chemical/Organic Synthesis | Structural Modification of Nucleoside Compounds | Employs acetyl groups as hydroxyl protecting groups to direct modifications (e.g., halogenation, acylation) at other positions on the purine base or sugar ring, followed by deprotection to yield the target product. |
| Pharmaceutical Industry | Active Pharmaceutical Ingredient (API) Manufacturing | Directly employed in the production of adenosine API via alkaline hydrolysis to remove acetyl protecting groups, followed by purification to obtain high-purity adenosine. |
Manufacturing Quality Control of 2',3',5'-Tri-O-acetyl-D-adenosine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | A reversed-phase C18 chromatographic column is used with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (e.g., at 254 nm) for detection. It effectively separates 2',3',5'-triacetyl adenosine from its impurities (such as unacetylated intermediates or degradation products), enabling quantitative analysis and is the most commonly used method for purity testing. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR are used to identify the molecular structure. The accuracy of the triacetyl substitution positions is verified through chemical shifts, coupling constants, and integration ratios to confirm the structural integrity of the target compound. |
| Molecular Weight Determination | Mass Spectrometry (MS, ESI-MS or MALDI-TOF) | Electrospray ionization mass spectrometry (ESI-MS) or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) accurately determines the molecular weight, confirming the molecular formula as C₁₄H₁₈N₅O₇, which helps identify the presence of by-products or incorrect modifications. |
| Content Determination | Ultraviolet-Visible Spectrophotometry (UV-Vis) | The characteristic absorption peak at 260–265 nm is utilized for content determination via standard curve methods. It is suitable for rapid screening but is more susceptible to interference from impurities and is typically used as an auxiliary method. |
| Residual Solvent Detection | Gas Chromatography (GC) | This method detects residual organic solvents (e.g., ethyl acetate, toluene, acetone) from the synthetic process. Headspace or direct injection is employed with a capillary column and FID or MS detector, complying with ICH Q3A standards. |
| Moisture Content Determination | Karl Fischer Titration | This method precisely measures the moisture content in the sample, preventing water from affecting subsequent reactions or stability, and is a key method for moisture control in active pharmaceutical ingredients. |
| Melting Point Determination | Melting Point Apparatus Method | Differential scanning calorimetry (DSC) or a melting point apparatus is used to determine the melting temperature range (e.g., approximately 190–195 °C), providing preliminary insight into the substance's purity and crystallinity. |
| Impurity Analysis | HPLC-MS Coupling Technique | High-performance liquid chromatography coupled with mass spectrometry not only separates impurities but also identifies unknown impurity structures through mass spectral information, enhancing the comprehensiveness of impurity profiling and being suitable for quality research and stability studies. |
Technical Specifications of 2',3',5'-Tri-O-acetyl-D-adenosine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | -31.0 to -29.0° (c=1, in methanol) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2',3',5'-Tri-O-acetyl-D-adenosine
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| Lot/Batch Number | *Required fields | |
NMR Spectra of 2',3',5'-Tri-O-acetyl-D-adenosine
Safety Information of 2',3',5'-Tri-O-acetyl-D-adenosine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2',3',5'-Tri-O-acetyl-D-adenosine
Industrial 2',3',5'-Tri-O-acetyl-D-adenosine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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