Methyl L-histidinate dihydrochloride Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 7389-87-9 |
| Product name | Methyl L-histidinate dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Methyl L-histidinate dihydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl L-histidinate dihydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl L-histidinate dihydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Chemical synthesis, condensation reactions |
| Biochemical research | Protein structure and function studies | Ligand binding assays, enzyme activity assays |
| Personal care | Antioxidant or skin-conditioning agent | Chemical modification, formulation incorporation |
| Food industry | Nutritional fortificant | Chemical synthesis, compounding technology |
| Agriculture | Biostimulant or feed additive | Fermentation process, post-synthesis compounding |
Manufacturing Quality Control of Methyl L-histidinate dihydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration with NaOH | Quantifies L-histidine methyl ester dihydrochloride by neutralizing HCl counterions with standardized NaOH using potentiometric or indicator endpoint detection. |
| Water Content | Karl Fischer Titration | Measures water content based on stoichiometric reaction of iodine with water in a methanol-based reagent under controlled electrochemical or volumetric conditions. |
| Residual Solvents (Methanol, Ethyl Acetate) | Gas Chromatography (GC) with FID | Separates and quantifies volatile organic solvents using capillary GC column and flame ionization detection against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace heavy metals via plasma ionization followed by mass spectrometric quantification with isotope dilution or external calibration. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Determines chloride ions by titration with silver nitrate, monitored by silver-selective electrode detecting the precipitation endpoint. |
| Optical Rotation | [α]D Measurement using Polarimetry | Measures specific optical rotation at 589 nm to confirm chiral integrity and enantiomeric purity of L-configuration. |
| Related Substances (Impurities) | HPLC with UV Detection | Separates and quantifies structurally related impurities (e.g., L-histidine, methyl ester mono-HCl, degradation products) using reversed-phase C18 column and UV detection at 210 nm. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic residue after controlled high-temperature ashing (700–800 °C) and weighing. |
| pH of Aqueous Solution (1% w/v) | pH Potentiometry | Measures hydrogen ion activity in a defined aqueous solution using calibrated pH electrode and reference buffer. |
| Microbial Limits | Membrane Filtration + Culture Enumeration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per pharmacopoeial methods (USP <61>/<62>). |
Technical Specifications of Methyl L-histidinate dihydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 235-240 °C (decomposes) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Optical Rotation | +11.0 to +13.0 ° (c=1, 1M HCl) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Methyl L-histidinate dihydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl L-histidinate dihydrochloride
Safety Information of Methyl L-histidinate dihydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl L-histidinate dihydrochloride
Industrial Methyl L-histidinate dihydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply