7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 73942-87-7 |
| Product name | 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing selective α1-adrenergic receptor antagonists (e.g., analogues of alfuzosin) | Multi-step organic synthesis: construction of the benzodiazepine core via N-alkylation, cyclization, and deprotection |
| Pharmaceutical R&D | Structural probe for studying binding affinity of benzodiazepine derivatives toward the 5-HT2A receptor | Modification of lead compounds for molecular docking and in vitro receptor binding assays |
| Chemical Research | Building block for novel heterocyclic scaffolds, supporting the development of asymmetric catalytic cyclization methodologies | Validation of advanced synthetic methods, including palladium-catalyzed C–H activation/cyclization and chiral phosphoric acid-catalyzed imine cycloaddition |
Manufacturing Quality Control of 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, dichloromethane) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generated electrochemically in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled incineration at 500-600 C followed by weighing of the ash. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube method. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension via Mie scattering theory using laser diffraction instrument. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined aqueous suspension using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli) using membrane filtration and selective agar culture. |
Technical Specifications of 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 148–152 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
Safety Information of 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
Industrial 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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