China Factory Direct
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| CAS number | 7425-53-8 |
| Product name | ETHYL 4-IODOBUTYRATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Precursor for synthesizing antitumor agents, antimicrobial agents, and radioactive tracers | Used as an iodinated alkylating reagent in nucleophilic substitution reactions to construct iodine-containing side chains in bioactive molecules |
| Organic Synthesis | Preparation of 4-iodobutyric acid, 4-aminobutyric acid derivatives, and cyclic compounds (e.g., pyrrolidones) | Hydrolyzed under basic conditions to yield 4-iodobutyric acid; nitrogen functionality introduced via palladium-catalyzed coupling (e.g., Heck or Suzuki reactions) or aminolysis; or cyclized via intramolecular nucleophilic substitution |
| Materials Science | Iodinated building block for liquid crystal monomers and functional polymers | Long-chain iodinated spacers incorporated into materials via free-radical polymerization or click chemistry (e.g., azide–alkyne cycloaddition) to modulate mesophase behavior |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies 4-iodobutyric acid ethyl ester peak area against a calibration curve using an internal or external standard. |
| Related Substances | Gas Chromatography (GC) with FID detection | Detects and quantifies structurally related impurities (e.g., unreacted acid, alcohol, iodinated by-products) based on retention time and relative response. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Measures volatile solvents (e.g., ethanol, toluene, dichloromethane) via equilibrium partitioning into headspace followed by GC separation. |
| Water Content | Karl Fischer Titration | Determines water content via stoichiometric reaction between water and Karl Fischer reagent (iodine, sulfur dioxide, base, and alcohol). |
| Acid Value | Acid-Base Titration with NaOH | Measures free carboxylic acid impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Iodine Content | Oxidimetric Titration (Sodium Thiosulfate after Bromination) | Oxidizes iodide to iodine using bromine, then titrates liberated iodine with standardized sodium thiosulfate solution. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of the liquid sample against standard references under controlled lighting. |
| Refractive Index | Refractometry | Measures bending of light through the sample at specified temperature to assess purity and consistency. |
| Density | Digital Density Meter | Determines mass per unit volume using oscillating U-tube principle for batch-to-batch uniformity verification. |
| Boiling Point | Distillation (Micro or Semi-micro) | Determines temperature range at which the compound distills under reduced pressure, indicating volatility and presence of low- or high-boiling impurities. |
| Heavy Metals | ICP-OES | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg, As) after acid digestion by measuring element-specific atomic emission intensities. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue remaining after high-temperature incineration of a weighed sample. |
| Test Item | Specification |
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| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.515–1.525 |
| Relative Density (20°C/25°C) | 1.48–1.52 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.