China Factory Direct
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| CAS number | 74457-86-6 |
| Product name | 2-Fluoro-4-methoxyacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for antidepressants, antipsychotics, and other active pharmaceutical ingredients | Introduces the fluorinated acetophenone moiety via Friedel–Crafts acylation, nucleophilic substitution, or reduction |
| Agrochemicals | Precursor to fluorinated active ingredients in insecticides and herbicides | Constructs fluorinated heterocycles or side-chain structures via halogen exchange, condensation, or cyclization |
| Organic Synthesis | Aromatic fluorinated ketone used in C–C bond formation and functional group transformations | Undergoes cross-coupling, Wittig reactions, or α-halogenation under transition-metal catalysis or basic conditions |
| Materials Science | Used to synthesize fluorinated liquid crystal monomers or optoelectronic material precursors | Modulates molecular polarity and orientation via esterification, etherification, or polymerization to integrate methoxy and ketone carbonyl groups |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Identifies and quantifies impurities by retention time and peak area relative to main peak using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., acetone, methanol, ethyl acetate) via headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Acid Value | Acid-Base Titration | Determines free acidic impurities by titration with standardized potassium hydroxide solution in ethanol/isopropanol mixture. |
| Heavy Metals | ICP-OES | Quantifies total heavy metal content (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against standard white background under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Measures volatile matter loss by weighing sample before and after drying at specified temperature and vacuum conditions. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after high-temperature ashing and subsequent weighing. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral compounds in solution using sodium D-line at specified concentration and path length. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-red solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.