N-Boc-trans-4-Hydroxy-L-proline methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 74844-91-0 |
| Product name | N-Boc-trans-4-Hydroxy-L-proline methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Boc-trans-4-Hydroxy-L-proline methyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Boc-trans-4-Hydroxy-L-proline methyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Boc-trans-4-Hydroxy-L-proline methyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used as a structural building block for synthesizing peptides, protease inhibitors, and other bioactive molecules |
| Pharmaceuticals | Anticancer drug research | Applied in constructing proline-containing cyclic peptides with anticancer activity |
| Pharmaceuticals | Neurological drug synthesis | Employed as a chiral building block for synthesizing precursors of antidepressant and anxiolytic agents |
| Chemical synthesis | Chiral auxiliaries | Used as a chiral inducer in asymmetric synthesis to control product stereochemistry |
| Chemical synthesis | Solid-phase peptide synthesis | Applied as a protected amino acid derivative for constructing specific peptide sequences in solid-phase synthesis |
| Research | Molecular structure studies | Used in NMR spectroscopy or X-ray crystallography to determine protein and peptide conformations |
| Research | Enzyme substrate or inhibitor design | Applied in studying the catalytic mechanisms of proline-related enzymes and developing inhibitors |
Manufacturing Quality Control of N-Boc-trans-4-Hydroxy-L-proline methyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities relative to the main peak using gradient reverse-phase chromatography. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg) by mass spectrometric detection of elemental ions. |
| Residual Palladium | ICP-MS | Specific quantification of Pd catalyst residue using isotope-specific mass detection. |
| Chloride Content | Ion Chromatography | Separation and conductivity-based detection of chloride anions in aqueous extract. |
| Residual Acids (e.g., TFA) | HPLC-UV | Detection of acidic impurities by reversed-phase HPLC with UV detection after derivatization or direct analysis. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size via light scattering pattern generated by dispersed particles in air. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs under controlled heating. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens using selective culture media. |
Technical Specifications of N-Boc-trans-4-Hydroxy-L-proline methyl ester
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -65° to -69° (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 85°C to 89°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Boc-trans-4-Hydroxy-L-proline methyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Boc-trans-4-Hydroxy-L-proline methyl ester
Safety Information of N-Boc-trans-4-Hydroxy-L-proline methyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-Boc-trans-4-Hydroxy-L-proline methyl ester
Industrial N-Boc-trans-4-Hydroxy-L-proline methyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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