1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 74853-08-0 |
| Product name | 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antidepressants and 5-HT receptor modulators | Prepared via condensation of 4-phenylenediamine with a 4-hydroxyphenylpiperazine derivative, followed by purification |
Manufacturing Quality Control of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible foreign matter under natural light or standard lighting conditions. |
| Identification | Infrared Spectroscopy (FT-IR) | Compare the sample spectrum with reference spectra to confirm the positions of characteristic absorption peaks for functional groups such as —NH₂, —OH, and piperazine rings. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Analyze the chemical environment of protons and carbon atoms in the molecular structure via proton and carbon NMR spectra to verify the compound's structure. | |
| Mass Spectrometry (MS) | Determine the molecular ion peak ([M+H]⁺ or [M-H]⁻) and confirm whether the molecular weight matches the theoretical value. | |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 254 nm or 280 nm), and calculate the main component content using the external standard method or area normalization method. |
| Impurity Analysis | HPLC Method | Detect related substances, including synthesis intermediates and degradation products. Impurity limits are determined by comparison with reference standards or peak area thresholds. |
| Water Content | Karl Fischer Titration | Accurately determine the water content in the sample using titration; suitable for trace moisture detection. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents that may remain from the manufacturing process (e.g., methanol, ethanol, dichloromethane, DMF), in compliance with ICH Q3C guidelines. |
| Melting Point | Melting Point Apparatus Method | Determine the melting temperature range using an automatic or capillary melting point apparatus to preliminarily assess purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure the levels of heavy metals such as lead, cadmium, mercury, and arsenic, in accordance with pharmacopeia or safety standards. |
| Sulfated Ash | Sulfuric Acid Ashing Method | Determine the amount of inorganic impurities by weighing the residue after high-temperature ashing of the sample with sulfuric acid. |
| Solubility | Solubility Test | Observe the solubility of the sample in various solvents such as water, ethanol, and DMSO to assist in evaluating its physicochemical properties. |
Technical Specifications of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 195–199 °C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
Safety Information of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
Industrial 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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