China Factory Direct
|
|
| CAS number | 74863-82-4 |
| Product name | 3-Methyl-8-quinolinesulphonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor drugs | Used to synthesize quinoline derivatives with antitumor activity |
| Pharmaceuticals | Intermediate in the synthesis of antiviral drugs | Applied to prepare quinoline-based antiviral compounds |
| Pharmaceuticals | Key intermediate in the synthesis of antibacterial drugs | Applied to synthesize quinoline sulfonamide drugs with antibacterial activity |
| Chemical Industry | Organic synthesis reagent | Participates in sulfonation reactions to construct sulfonamide structures |
| Materials Science | Synthesis of functional dyes | Used to prepare quinoline-based intermediates for functional dyes |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, appearance, and presence of visible impurities under natural light or standard light sources. Typically appears as white to off-white crystalline powder. |
| Purity (Content) | HPLC (High-Performance Liquid Chromatography) | Use a reverse-phase C18 column with a UV detector (e.g., 254 nm), and determine the main component content via external standard method or area normalization method to assess purity. |
| Structural Confirmation | NMR (Nuclear Magnetic Resonance Spectroscopy) | Use 1H-NMR and 13C-NMR to analyze the molecular structure and confirm the chemical environment of hydrogen and carbon atoms matches the target structure. |
| Structural Confirmation | Mass Spectrometry (MS) | Use ESI (Electrospray Ionization) or EI (Electron Impact) mass spectrometry to determine the molecular ion peak and verify that the molecular weight matches the target compound. |
| Residual Solvent | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethyl acetate) from the production process according to pharmacopoeia or related standards (e.g., ICH Q3C). |
| Moisture Content | Karl Fischer Titration | Quantitatively determine the moisture content in the sample using Karl Fischer reagent. Suitable for sulfon chloride compounds sensitive to moisture. |
| Melting Point | Melting Point Determination | Determine the melting temperature range using a melting point apparatus or capillary method to preliminarily assess purity and material properties. |
| Chlorine Content (Active Chlorine) | Titration (e.g., Argentometric Method) | Determine the effective chlorine content by titrating the released chloride ions after hydrolysis with a silver nitrate standard solution, indirectly reflecting reaction activity. |
| Impurity Analysis | HPLC-UV or LC-MS | Separate and identify related substances (e.g., raw material residues, degradation products) using reference standards or peak area thresholds to control impurity limits. |
| Particle Size Distribution | Laser Particle Size Analysis | Applicable for solid samples; measure particle size distribution, which affects solubility and subsequent reaction performance (e.g., in synthesis applications). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Identification (NMR) | Conforms to reference standard |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.