China Factory Direct
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| CAS number | 7517-19-3 |
| Product name | Methyl L-leucinate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used as an intermediate in the synthesis of peptide-based drugs, enabling amino acid modification |
| Biochemistry | Peptide synthesis | Applied in solid-phase peptide synthesis as a protected amino acid derivative |
| Chemical synthesis | Organic synthesis reagent | Employed as a nucleophile or catalyst in organic synthesis |
| Food industry | Food additive | Utilized in the preparation of amino acid-based nutritional fortifiers |
| Agriculture | Pesticide formulation | Serves as a structural building block or stabilizer in pesticide synthesis |
| Materials science | Functional material synthesis | Applied in the preparation of bioactive functional polymeric materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies L-leucine methyl ester hydrochloride by reversed-phase HPLC with UV detection at 200-220 nm, using a calibrated standard. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Residual Solvents | GC-FID | Identifies and quantifies common organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (Pb, Cd, Hg, As, etc.) after acid digestion by optical emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Determines chloride ions using silver nitrate titrant and silver/silver chloride indicator electrode. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| pH (1% aqueous solution) | pH Meter | Determines acidity of a 1% w/v aqueous solution using calibrated pH electrode in accordance with USP/EP general chapter. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., L-leucine, methyl ester hydrolysis products) using gradient HPLC with UV detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic residue after high-temperature ashing (700-800 °C) and weighing of the residual ash. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, confirming identity and purity based on sharpness and agreement with reference value. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per pharmacopoeial methods. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using light scattering principles and Mie theory. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 220-225°C (decomposes) |
| Optical Rotation | +12.0 to +14.0° (c=1, 6M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.