L-Prolinamide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7531-52-4 |
| Product name | L-Prolinamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for L-Prolinamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk L-Prolinamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of L-Prolinamide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral synthon or intermediate in the production of antiviral agents (e.g., HIV protease inhibitors) and alkaloids | Organic synthesis, typically involving asymmetric synthesis or enzyme-catalyzed reactions |
| Biochemistry | Employed in peptide synthesis as a building block or protecting group | Solid-phase or solution-phase peptide synthesis |
| Research & Development | Utilized as a reagent or reference standard for chiral analysis and biological activity studies | Laboratory-scale chemical synthesis or separation and purification |
| Agrochemicals | Potentially applied as an intermediate in the synthesis of pesticides or plant growth regulators | Organic synthesis processes, possibly including condensation or functionalization reactions |
Manufacturing Quality Control of L-Prolinamide
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of L-prolinamide and compare it with the reference spectrum to confirm characteristic functional group peaks (such as amide C=O, N–H, etc.), used for structural confirmation. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze the chemical shifts and coupling constants of hydrogen atoms in the molecule using NMR technology, and verify the compound structure by comparison with a standard spectrum. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-water or methanol-phosphate buffer) under isocratic or gradient elution, and a UV detector (typically around 210 nm) to quantitatively analyze the main component. |
| Acid-Base Titration | Utilize the weak basicity (secondary amine) or weak acidity (amide group) of L-prolinamide to determine purity via non-aqueous titration or potentiometric titration; suitable as an alternative method when chromatographic conditions are not available. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use a high-sensitivity HPLC method (often compatible with assay but with optimized separation conditions) to separate and detect process impurities, degradation products, etc., and calculate impurity levels using area normalization or correction factors. |
| Specific Optical Rotation | Polarimetry | Prepare a solution of L-prolinamide at a defined concentration and measure its optical rotation at a specified wavelength (typically sodium D line, 589 nm) and temperature, then calculate the specific optical rotation to verify optical purity and L-configuration. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Loss on Drying at Atmospheric Pressure | Dry the sample to constant weight at a specified temperature (e.g., 105°C) and measure the weight loss to assess moisture and volatile content. |
| Sulfated Ash (Residue on Ignition) | Residue on Ignition Test | Ignite the sample at high temperature (typically 700–800°C), then weigh the remaining inorganic residue to control total inorganic impurities. |
| Heavy Metals | Thioacetamide Method (or ICP-MS) | According to pharmacopoeial general chapters, determine residual heavy metal elements (e.g., lead, cadmium, mercury, arsenic) by colorimetric reaction (thioacetamide generates hydrogen sulfide in acidic conditions, forming precipitates with heavy metal ions) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS). |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric Karl Fischer titration for specific determination of water content; suitable for samples containing crystalline water or hygroscopic substances. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1% or 0.1 mol/L), and measure the pH using a calibrated pH meter to reflect the presence of free acid/base impurities. |
Technical Specifications of L-Prolinamide
| Test Item | Specification |
|---|---|
| Appearance | White to orange to green crystalline powder |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 188~192°C |
| Optical Rotation | -103~ -109° (c=1, in H2O) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of L-Prolinamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of L-Prolinamide
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Industrial L-Prolinamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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