1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 75338-42-0 |
| Product name | 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 75338-42-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 75338-42-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 75338-42-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate for synthesizing quinolone antibiotics (e.g., ofloxacin) | Used as a key intermediate in multistep organic synthesis, typically involving esterification, cyclization, or substitution reactions to construct the quinolone core structure |
| Pharmaceutical R&D | Lead compound or structural modification template in medicinal chemistry research | Applied in structure–activity relationship (SAR) studies; antimicrobial activity and pharmacokinetic properties are optimized by introducing diverse substituents at the carboxylic acid or fluorinated aryl positions |
| Chemical Reagents | High-purity organic building block | Employed under anhydrous, oxygen-free conditions for nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to construct complex fluorinated heterocyclic molecules |
Manufacturing Quality Control of 75338-42-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 275 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold limits. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., acetone, methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine total water content based on stoichiometric reaction. |
| Residue on Ignition | Gravimetric Analysis | Mass measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic sulfate content by ignition of sample with sulfuric acid followed by weighing of residual ash. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine volume-weighted particle size distribution. |
| pH of Aqueous Suspension | Potentiometric Measurement | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic bacteria, yeasts, and molds by filtration, membrane transfer to selective media, and colony counting. |
Technical Specifications of 75338-42-0
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 228–232°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 75338-42-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 75338-42-0
Packaging of 75338-42-0
Industrial 75338-42-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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