1-BOC-INDOLE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 75400-67-8 |
| Product name | 1-BOC-INDOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-BOC-INDOLE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-BOC-INDOLE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-BOC-INDOLE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing active pharmaceutical ingredients (APIs) containing indole motifs, such as kinase inhibitors and 5-HT receptor modulators | Applied in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) under inert atmosphere, or in alkylation/acylation modifications following N-deprotection |
| Organic Synthesis | Protects the indole nitrogen atom to enhance regioselectivity and suppress side reactions | BOC group is selectively introduced onto the indole N–H under basic conditions (e.g., using NaH or DIPEA) with isobutylene chloride or di-tert-butyl dicarbonate (Boc₂O) |
| Materials Science | Building block for functionalized organic semiconductor molecules in OLED or OFET material design | Used as an electron-donating unit; undergoes derivatization (e.g., halogenation, boronic esterification) prior to copolymerization or multi-step coupling assembly |
Manufacturing Quality Control of 1-BOC-INDOLE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., unreacted indole, BOC-anhydride derivatives) via gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., dichloromethane, ethyl acetate) using headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric electrochemical reaction. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual non-volatile matter. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection after sample dissolution. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral purity and identity; requires solution in specified solvent and path length. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity against established reference standard under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using Mie scattering theory and diffraction pattern analysis. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized aqueous slurry (e.g., 1% w/v) using calibrated pH electrode. |
Technical Specifications of 1-BOC-INDOLE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 52–56°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-BOC-INDOLE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-BOC-INDOLE
Packaging of 1-BOC-INDOLE
Industrial 1-BOC-INDOLE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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