1H-INDAZOLE-7-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 755752-82-0 |
| Product name | 1H-INDAZOLE-7-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1H-INDAZOLE-7-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1H-INDAZOLE-7-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1H-INDAZOLE-7-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used in the synthesis of biologically active indazole compounds as a key building block for drug molecules |
| Pharmaceutical R&D | Kinase inhibitor development | Applied in the preparation of antitumor candidate drugs, such as protein kinase inhibitors (e.g., PI3K, mTOR) |
| Chemical research | Functionalized derivative synthesis | Subjected to amidation, esterification, and other reactions via the carboxyl functional group for structural modification and structure–activity relationship studies |
Manufacturing Quality Control of 1H-INDAZOLE-7-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorbance at specific wavelength using reversed-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection against reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine consumption in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after ignition at 500-600 C following sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube method. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard references. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry powder by analyzing angular scattering pattern of laser beam. |
| Bulk Density | ASTM D1895 | Determines mass per unit volume of freely settled powder using standardized cylinder and tapping procedure. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
Technical Specifications of 1H-INDAZOLE-7-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 215–219 °C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1H-INDAZOLE-7-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1H-INDAZOLE-7-CARBOXYLIC ACID
Safety Information of 1H-INDAZOLE-7-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1H-INDAZOLE-7-CARBOXYLIC ACID
Industrial 1H-INDAZOLE-7-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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