(R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 75638-15-2 |
| Product name | (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing peptide-based drugs and antibiotics | Used as a protected amino acid monomer in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) for coupling reactions |
| Pharmaceuticals | Key chiral building block for synthesizing β-lactam antibiotics, such as carbapenems | Employed in deprotection and coupling steps to construct the β-lactam ring core structure |
| Pharmaceuticals | Non-natural amino acid unit for antiviral or antitumor active molecules | Incorporated into the target molecular scaffold following Boc deprotection, then assembled via catalytic hydrogenation or acidolysis |
| Biotechnology | Tool compound for enzymatic asymmetric synthesis studies | Applied as substrate or inhibitor probe in enzymatic systems to evaluate stereoselective transformation efficiency |
| Chemical R&D | Chiral source for constructing α-amino acid fragments in complex natural products or drug molecules | Utilized in multi-step synthesis involving functional group transformations (e.g., esterification, amidation) with stereochemical integrity maintained |
Manufacturing Quality Control of (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation and quantification of (R)- and (S)-enantiomers using a chiral stationary phase; enantiomeric excess calculated from peak areas. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to stoichiometrically determine water content in the sample. |
| Residual Solvents | GC-FID | Headspace or direct-injection GC with flame ionization detection to quantify common solvents (e.g., THF, ethyl acetate, methanol) against calibration standards. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic detection for high sensitivity and specificity. |
| Residual Chloride | Ion Chromatography (IC) | Separation and quantification of chloride anion on an anion-exchange column with suppressed conductivity detection. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Comparison of sample solution (in specified solvent) against platinum-cobalt standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed via optical detection as solid converts to liquid; correlates with crystallinity and purity. |
| Residual TFA (Trifluoroacetic Acid) | GC-ECD | Gas chromatographic separation with electron-capture detection for selective and sensitive quantification of TFA. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volume-weighted particle size distribution in dispersed solid sample. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Mass loss measured after controlled heating (e.g., 105 °C, 2 h) under defined atmosphere (N₂ or air). |
Technical Specifications of (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C to 132°C |
| Optical Rotation | +12.5° to +13.5° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
Safety Information of (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate
Industrial (R)-2-((tert-Butoxycarbonyl)aMino)propanoic acid hydrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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