2-Chloropyrimidine-4-carbonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 75833-38-4 |
| Product name | 2-Chloropyrimidine-4-carbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloropyrimidine-4-carbonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloropyrimidine-4-carbonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloropyrimidine-4-carbonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the broad-spectrum fungicide azoxystrobin | Condensation with methyl methoxyacrylate under basic conditions, followed by cyclization and purification to yield azoxystrobin |
| Pesticides | Intermediate in the synthesis of the fungicide trifloxystrobin | Catalyzed condensation with benzaldehyde oxime to construct the oxime ether structure |
| Pharmaceuticals | Synthetic intermediate for anticancer drug candidates | Used to construct the pyrimidine heterocyclic scaffold; participates in coupling or nucleophilic substitution reactions to prepare targeted kinase inhibitors |
| Materials | Functionalization intermediate for organic optoelectronic materials | Cyanide group conversion introduces electron-accepting moieties for synthesizing OLED emissive or electron-transport layer materials |
Manufacturing Quality Control of 2-Chloropyrimidine-4-carbonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching with reference standards or relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, toluene) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using isotopic dilution or external calibration. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anion on an anion-exchange column with suppressed conductivity detection, calibrated using NaCl standards. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-750 C followed by weighing of residual inorganic ash after treatment with sulfuric acid. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature at which solid phase fully converts to liquid under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of bulk sample against established reference standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine volume-weighted particle size distribution in dispersed dry or wet samples. |
| Bulk Density | Tap Density Measurement | Mass per unit volume determined after standardized tapping (e.g., 100 taps) of a known mass in a calibrated cylinder. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode pH meter. |
Technical Specifications of 2-Chloropyrimidine-4-carbonitrile
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 76–79°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloropyrimidine-4-carbonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloropyrimidine-4-carbonitrile
Safety Information of 2-Chloropyrimidine-4-carbonitrile
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloropyrimidine-4-carbonitrile
Industrial 2-Chloropyrimidine-4-carbonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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