4-Amino-2-bromopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7598-35-8 |
| Product name | 4-Amino-2-bromopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-2-bromopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-2-bromopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-2-bromopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor and antiviral drugs | Introduced into drug molecular structures via coupling or substitution reactions |
| Agrochemicals | Active ingredient in fungicides and insecticides | Integrated as a heterocyclic structural unit in condensation or cyclization reactions |
| Materials Science | Preparation of organic light-emitting diode (OLED) materials or ligands | Complexed with metal ions as a ligand, or polymerized to produce functional materials |
| Dyes | Synthesis of specialty dyes or fluorescent labels | Conjugated systems constructed via diazotization or condensation reactions |
| Research Reagents | Reference standard for organic synthesis or chemical analysis | Used as a substrate in cross-coupling reactions such as Suzuki coupling |
Manufacturing Quality Control of 4-Amino-2-bromopyridine
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Appearance and Properties | Visual Inspection + Physical Property Determination | Observe sample color and state (typically white to off-white crystalline powder), determine melting point range (literature value ~120–125°C), and assess conformity with specifications. |
| Content Determination (Active Ingredient) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column, water-acetonitrile or methanol-buffer salt (e.g., phosphate) as mobile phase, UV detector (λ ≈ 254 nm) for detection, external standard quantification method to ensure active ingredient content ≥98.0%. |
| Impurity Profile Analysis | HPLC-UV or HPLC-MS | Separate potential impurities (such as unreacted starting material 2-bromopyridine, dibromo derivatives, oxidation products, debromo products, etc.) using gradient elution; control single impurity ≤0.5%, total impurities ≤1.0% by peak area normalization or reference standard external standard method. |
| Bromine Content | Combustion Ion Chromatography (CIC) or Oxygen Bomb Combustion + Ion Chromatography | The sample is combusted in an oxygen bomb and converted to bromide ions, which are then measured by ion chromatography for Br⁻ concentration. Compare with theoretical value (~37.5%) to verify molecular structural integrity. |
| Moisture Content | Karl Fischer Titration (KF) | Determine moisture content using coulometric or volumetric Karl Fischer reagent, controlled at ≤0.5% (compliant with API standards), to prevent hydrolysis or hydration effects on stability. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with DB-624 or HP-INNOWAX column, FID detection, to analyze residual solvents (e.g., methanol, ethanol, acetonitrile, DMF), meeting ICH Q3C limits. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine lead (Pb), cadmium (Cd), arsenic (As), mercury (Hg), etc., after acid digestion; control within ≤10 ppm (compliant with pharmacopoeia standards). |
| Chloride/Sulfate Impurities | Colorimetric Method or Ion Chromatography | Detect chloride via silver nitrate turbidity method or use ion chromatography to detect chloride and sulfate ions; control within ≤0.1% (to avoid halogenated byproduct contamination). |
| pH Value (Aqueous Solution) | pH Meter Measurement | Prepare a 1% aqueous solution of the sample and measure pH using a calibrated pH meter; control pH between 5.0–7.5 to evaluate acid-base stability and potential hydrolysis tendency. |
| Particle Size Distribution (if applicable) | Laser Diffraction Method | For raw materials requiring powder form, determine D50, D90, etc., particle size parameters to ensure process consistency (especially affecting dissolution in formulations). |
| UV-Visible Absorption Spectrum | UV-Vis Spectrophotometry | Prepare a solution in ethanol or methanol and measure absorption characteristics in the 200–400 nm wavelength range (e.g., λmax ≈ 260–280 nm) for preliminary identification and purity screening. |
Technical Specifications of 4-Amino-2-bromopyridine
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 72–76°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-2-bromopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-2-bromopyridine
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Industrial 4-Amino-2-bromopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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