China Factory Direct
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| CAS number | 76-60-8 |
| Product name | Bromocresol green |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Analytical Chemistry | Acid-base indicator (pH range 3.8–5.4; color change from yellow to blue) | Used in titration analysis, preparation of pH test papers, and pH monitoring of buffer solutions |
| Clinical Testing | Quantitative determination of serum albumin (bromocresol green colorimetric method) | Forms a blue-green complex specifically with albumin; absorbance measured at 628 nm |
| Microbiology | pH indicator in culture media | Added to selective or differential media (e.g., bromocresol green lactose agar) to indicate color changes resulting from bacterial acid production during fermentation |
| Pharmaceutical Industry | pH indicator for quality control of active pharmaceutical ingredients (APIs) and formulations | Applied to verify pH adjustment in formulations (e.g., injectables, oral solutions) and to determine reaction endpoints for intermediates |
| Environmental Monitoring | Indicator for total alkalinity or carbonate system titrations in water analysis | Indicates the second endpoint (pH ≈ 4.5) in titrations of carbonate-buffered systems |
| Test Item | Common Test Method | Method Description |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state of the sample. Bromocresol green should be a brownish-green or dark red powder, free from visible impurities. |
| Identification | UV-Visible Spectrophotometry | Prepare a solution of specified concentration in ethanol or water, and scan absorption peaks within 200–800 nm range. Bromocresol green shows characteristic absorption peaks under acidic (e.g., ~420 nm) and alkaline (e.g., ~615 nm) conditions, confirming its structural identity. |
| Assay | UV-Visible Spectrophotometry | Measure absorbance at the maximum wavelength (e.g., ~615 nm under alkaline conditions) and calculate active ingredient content using a standard curve. Compliance with pharmacopoeial or enterprise standards is required (e.g., ≥98.0%). |
| Loss on Drying | Thermogravimetric Analysis (Oven Method) | Weigh sample and dry in an oven at 105°C to constant weight; calculate percentage weight loss. Typically limited to ≤3.0%. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | Char the sample at high temperature, treat with sulfuric acid, then ignite to constant weight and weigh the residue. Generally limited to ≤0.5%. |
| pH Indicator Performance | pH Titration with Color Comparison | Add bromocresol green to buffer solutions of varying pH (pH 3.8–5.4) and observe color change (yellow → blue-green), verifying that the transition range meets specifications. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Colorimetry | Determine levels of heavy metals such as lead and arsenic according to pharmacopoeial methods. Commonly uses sulfide colorimetry or AAS for quantification; must comply with limits (e.g., Pb ≤ 10 ppm). |
| Volatile Organic Impurities | Gas Chromatography (GC) | Detect residual solvents or other volatile impurities, particularly organic solvents used during synthesis (e.g., ethanol, acetone). |
| Purity (Related Substances) | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC to assess main peak purity and detect impurity peaks. Calculate areas of impurity peaks; total impurities generally limited to ≤1.0%. |
| Test Item | Specification |
|---|---|
| Appearance | Green crystalline powder |
| Purity | >=98.5% |
| Melting Point | 215-218°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.