5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 76006-08-1 |
| Product name | 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of BCR-ABL inhibitors (e.g., bosutinib) | Construction of the pyrazolopyridine scaffold via nucleophilic substitution |
| Pharmaceuticals | Raw material for Janus kinase (JAK) inhibitor anti-inflammatory drugs | Coupling reactions and functional group modification |
| Pharmaceuticals | Key building block in the synthesis of anticancer or immunomodulatory agents | Aromatic ring chlorination or Suzuki coupling |
Manufacturing Quality Control of 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode-array detection; relative retention times and spectral matching used for qualification. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Ion Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection with standard calibration. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measured by controlled heating of sample in capillary tube; onset and range indicate crystallinity and purity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral compounds in solution, indicating enantiomeric composition if applicable. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed particles using Mie theory to calculate size distribution based on light scattering patterns. |
| Bulk Density | Tap Density Measurement | Determination of mass per unit volume after standardized tapping of a known powder mass in a graduated cylinder. |
| Microbial Contamination | Membrane Filtration | Quantitative recovery of viable microorganisms from sample solution by filtration, followed by incubation on selective agar media. |
Technical Specifications of 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.5% (LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 248-252°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
Safety Information of 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
Industrial 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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