(R)-(1-(3-nitrophenyl))ethanol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 76116-24-0 |
| Product name | (R)-(1-(3-nitrophenyl))ethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-(1-(3-nitrophenyl))ethanol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-(1-(3-nitrophenyl))ethanol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-(1-(3-nitrophenyl))ethanol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing β-blocker drugs (e.g., nebivolol) | Produced via asymmetric synthesis, chiral resolution, or biocatalytic reduction of 3′-nitroacetophenone, followed by reduction, cyclization, and other steps to construct the target drug molecule |
| Fine Chemicals | Chiral auxiliary or ligand precursor | Serves as a structural building block for chiral catalysts or ligands, employed in the development of asymmetric catalytic reactions |
| Research | Chiral reference standard or model compound | Used in chiral chromatographic method development, mechanistic studies of stereoselective reactions, and teaching demonstrations |
Manufacturing Quality Control of (R)-(1-(3-nitrophenyl))ethanol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation on a chiral stationary phase (e.g., Chiralcel OD-H) with UV detection; ee calculated from peak area ratio of (R)- and (S)-enantiomers. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying common solvents (e.g., ethanol, toluene, ethyl acetate) against internal standard calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Digestion followed by inductively coupled plasma mass spectrometry for trace-level multi-element quantification with isotope dilution or external calibration. |
| Residual Inorganics (e.g., Cl⁻, SO₄²⁻) | Ion Chromatography (IC) | Anion-exchange chromatography with suppressed conductivity detection; quantifies ionic impurities derived from synthesis or workup. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Comparison of solution (e.g., 10% w/v in ethanol) against platinum-cobalt standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated digital melting point instrument per USP <741>. |
| Optical Rotation | [α]D | Measurement of specific rotation at 589 nm (Na-D line) using a digital polarimeter; confirms chiral integrity and batch-to-batch consistency. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Stability-indicating method with gradient elution; detects and quantifies degradants (e.g., nitrophenol, acetophenone derivatives) formed under acid/base/oxidative stress. |
| Residual Palladium (if Pd-catalyzed synthesis) | ICP-OES | Microwave-assisted acid digestion followed by inductively coupled plasma optical emission spectrometry for Pd quantification at 224.48 nm or 340.458 nm. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1:10 w/v in water) using calibrated pH electrode; indicates acidic/basic impurity burden. |
| Particle Size Distribution (if supplied as solid) | Laser Diffraction | Dry or wet dispersion followed by laser diffraction analysis to determine D10, D50, D90 values per ISO 13320. |
| Microbial Limits (if applicable for pharma-grade) | Membrane Filtration / TSA/SDA | Enumeration of aerobic bacteria, yeasts, and molds via membrane filtration and incubation on tryptic soy agar/sabouraud dextrose agar per USP <61>. |
Technical Specifications of (R)-(1-(3-nitrophenyl))ethanol
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% |
| Melting Point | 72-76°C |
| Optical Rotation | +18.5° to +20.5° (c=1, in chloroform) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-(1-(3-nitrophenyl))ethanol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-(1-(3-nitrophenyl))ethanol
Safety Information of (R)-(1-(3-nitrophenyl))ethanol
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-(1-(3-nitrophenyl))ethanol
Industrial (R)-(1-(3-nitrophenyl))ethanol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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