China Factory Direct
|
|
| CAS number | 76350-90-8 |
| Product name | 2-Methyl-3-biphenylmethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antihypertensive drug telmisartan | Used to construct the biphenyl structural unit of telmisartan via organic synthesis steps including Suzuki coupling, reduction, or alkylation |
| Fine Chemicals | Organic synthesis intermediate for preparing other functionalized biphenyl derivatives | Undergoes electrophilic substitution, oxidation, or condensation reactions to yield compounds with specific performance characteristics |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and a UV detector (e.g., 254 nm), with methanol-water or acetonitrile-water as the mobile phase under gradient or isocratic elution, for quantitative analysis of the active ingredient. |
| Purity Analysis | Gas Chromatography (GC) or HPLC | GC is suitable for samples with good volatility; HPLC is more commonly used for non-volatile or thermally unstable substances, assessing total purity by peak area normalization. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Uses ¹H-NMR and ¹³C-NMR to confirm molecular structure, including the positions of substituents and functional groups (e.g., hydroxymethyl, methyl, biphenyl moieties). |
| Functional Group Identification (Hydroxyl) | Fourier Transform Infrared Spectroscopy (FTIR) | Detects characteristic absorption peaks: a broad peak at 3200–3600 cm⁻¹ (O-H stretching vibration) and ~1050 cm⁻¹ (C-O stretching vibration), confirming the presence of hydroxymethyl group. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, headspace sampling-GC is used to detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) from the manufacturing process. |
| Moisture Content | Karl Fischer Titration | Precisely determines moisture content in the sample; suitable for hydroxyl-containing compounds, minimizing interference from side reactions. |
| Melting Point | Melting Point Apparatus | Determines the melting range using the capillary method, serving as a preliminary assessment of compound purity and consistency. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detects residual heavy metal elements such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmaceutical or industrial safety standards. |
| Related Substances (Impurities) | HPLC-UV or LC-MS | HPLC separates and detects potential impurities such as synthesis intermediates and degradation products; LC-MS can further identify the structures of impurities. |
| Polymorphic Form Analysis (if applicable) | X-Ray Diffraction (XRD) | If polymorphism is present, XRD can be used to identify the crystalline form and ensure batch-to-batch consistency. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.