N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 76379-01-6 |
| Product name | N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used as a key intermediate in the synthesis of peptides or chiral drugs to construct compounds with defined stereochemistry |
| Biochemistry | Peptide synthesis | Applied in solid-phase or solution-phase peptide synthesis as a protected amino acid derivative to facilitate subsequent deprotection and coupling reactions |
| Organic synthesis | Chiral synthesis reagent | Employed as a chiral auxiliary or building block in asymmetric synthesis to control stereoselectivity |
| Materials science | Functional material preparation | Utilized in the synthesis of polymeric or nanomaterials exhibiting biological activity or specific recognition functionality |
Manufacturing Quality Control of N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~210 nm. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase to resolve D- and L-enantiomers; detection by UV absorbance. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, ethyl acetate, toluene) via gas chromatographic separation with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine–sulfur dioxide redox reaction in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection with high sensitivity. |
| Residual Chloride | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing the temperature range over which solid-to-liquid phase change occurs under controlled heating. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution at 589 nm (Na D-line), confirming chiral integrity and concentration-corrected enantiomeric identity. |
| Related Substances | HPLC-UV (Gradient) | Detection and quantification of structurally related impurities (e.g., deprotected acid, ester hydrolysis products, diastereomers) using gradient elution and UV detection. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content after high-temperature incineration (700–800 °C) and weighing of residual non-volatile matter. |
| pH (1% w/v aqueous suspension) | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular variation in laser light scattering intensity from dispersed sample. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial compendia (e.g., USP <61>). |
Technical Specifications of N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | +20.0 to +23.0° (c=1, in 1M HCl) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
Safety Information of N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester
Industrial N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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