China Factory Direct
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| CAS number | 7651-82-3 |
| Product name | Isoquinolin-6-ol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of biologically active isoquinoline compounds, including anticancer, antimicrobial, and central nervous system agents | Target molecular scaffolds are constructed via organic synthesis methods such as nucleophilic substitution, reductive amination, or coupling reactions |
| Agrochemicals | Used as a synthetic intermediate for agrochemicals, including fungicides and insecticides | Involved in heterocycle modification or functional group transformation to build pesticide molecules with specific biological activity |
| Materials Science | Used in the preparation of organic optoelectronic materials or ligand precursors | Acts as a nitrogen-containing heterocyclic building block in metal complex synthesis or conjugated polymer construction |
| Research | Used as an organic synthesis building block for constructing compound libraries and structure–activity relationship (SAR) studies | Structural derivatization is carried out in the laboratory via multistep synthesis and heterocycle functionalization |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies 6-hydroxyisoquinoline by separation on a reversed-phase column and UV detection at ~254 nm, using external standard calibration. |
| Related Substances | HPLC-DAD | Detects and quantifies structurally related impurities (e.g., isoquinoline, quinoline derivatives) via HPLC with diode array detection and peak area comparison. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, toluene, DMF) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, As, Hg, etc.) after acid digestion using inductively coupled plasma mass spectrometry for ultra-trace detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after ignition at 700-750 C following sulfuric acid treatment; weight difference gives ash content. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral compounds; used to confirm identity and detect enantiomeric impurities if applicable. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine volume-weighted particle size distribution using Mie scattering theory. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies unknown or low-level volatile organic impurities using gas chromatography coupled with mass spectrometric detection. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.