China Factory Direct
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| CAS number | 76535-75-6 |
| Product name | DI-TERT-BUTYLPIPERAZINE-1,4-DICARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chemical Reagent and Intermediate | Used as a protected derivative of piperazine; the Boc group is selectively removed during multi-step organic synthesis to construct piperazine-containing drug molecules |
| Pharmaceutical Industry | Active Pharmaceutical Ingredient (API) Synthesis | Applied in the synthesis of active pharmaceutical ingredients (APIs), including antidepressants, antipsychotics, and anticancer agents |
| Chemical R&D | Hydroxylamine Group Protection | Employs tert-butoxycarbonyl (Boc) to protect nitrogen atoms on the piperazine ring during organic synthesis, preventing undesired side reactions |
| Biochemistry | Bioactive Molecule Modification | Serves as a linker or modifying group in the synthesis and modification of peptides, nucleotides, and other bioactive molecules |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., mono-Boc-piperazine, piperazine, di-Boc-piperazinedione) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., THF, DMF, toluene) based on retention time and flame ionization response relative to internal standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to quantify water content based on stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using mass spectrometric detection of elemental isotopes. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions eluted from an anion-exchange column after sample dissolution and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue remaining after high-temperature ashing (700-800 C) and cooling in a desiccator. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using controlled heating and visual observation of capillary tube sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration, path length, and wavelength (589 nm). |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volume-based particle size distribution in dispersed dry or wet samples. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined aqueous suspension (e.g., 1% w/v) using calibrated glass electrode system. |
| Microbial Limits | Membrane Filtration | Quantitative recovery and enumeration of aerobic microorganisms (bacteria, molds, yeasts) after filtration, membrane transfer, and incubation on appropriate agar media. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.