China Factory Direct
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| CAS number | 766-11-0 |
| Product name | 5-Bromo-2-fluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of antitumor drug intermediates | Used as a key intermediate in constructing fluorinated pyridine-containing targeted drug molecules |
| Agrochemical R&D | Intermediate for insecticide and herbicide synthesis | Participates in coupling reactions to prepare high-efficacy active ingredients, enhancing pesticide bioavailability |
| Organic Synthesis | Building block for fluorinated heterocyclic compounds | Introduces functional groups via cross-coupling reactions such as Suzuki and Negishi couplings |
| Materials Science | Functional polymer monomer | Applied in the preparation of fluorinated polymers with specialized electrical properties |
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural or standard lighting conditions. |
| Purity (Assay) | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column (e.g., C18) and UV detector (around 254 nm); quantifies the main component by comparing peak areas with a reference standard. |
| Gas Chromatography (GC) | Suitable for volatile organic compounds; separates components using a capillary column and detects them via FID; ideal for high-purity sample analysis. | |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Uses ¹H NMR and ¹⁹F NMR to confirm molecular structure, verifying the chemical environments of fluorine and hydrogen atoms. |
| Mass Spectrometry (MS) | Determines the molecular ion peak ([M]+) using ionization methods such as EI or ESI to confirm molecular weight and assist in structural identification. | |
| Residual Solvents | Gas Chromatography (GC) | Detects residual organic solvents (e.g., methanol, ethanol, dichloromethane) from manufacturing processes in accordance with ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration | Measures water content precisely using electrochemical titration; available in volumetric and coulometric methods. |
| Melting Point | Melting Point Apparatus | Determines the melting temperature range by heating the sample; used for preliminary assessment of purity and consistency (for solids). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects residual heavy metal elements such as lead, arsenic, and mercury to comply with pharmacopeial limits for impurities. |
| Chloride/Bromide Impurities | Ion Chromatography (IC) | Measures residual inorganic anions (e.g., Cl⁻, Br⁻) to evaluate by-products or degradation compounds. |
| Fluorine Content | Fluoride Ion-Selective Electrode or NMR | Quantitatively determines fluorine content in organic fluorine compounds to verify substitution position and content as expected. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.535–1.545 |
| Relative Density (20°C/25°C) | 1.62–1.64 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.