3-AMINO-1H-ISOINDOLE HYDROCHLORIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 76644-74-1 |
| Product name | 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing PDE5 inhibitors (e.g., tadalafil) | Prepared via multi-step organic synthesis, including acylation and cyclization, to yield the target active molecule |
| Organic Synthesis | Nitrogen-containing heterocyclic building block for constructing isoindoline scaffolds | Functional groups introduced via nucleophilic substitution, condensation, or metal-catalyzed coupling reactions |
| Drug Discovery | Structural modification in developing novel candidate drugs for neurological or cardiovascular indications | Core scaffold used in lead compound optimization for derivative synthesis and structure–activity relationship (SAR) studies |
Manufacturing Quality Control of 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies the main component by titration with standardized NaOH solution using an indicator or potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration | Measures water based on the stoichiometric reaction of iodine with sulfur dioxide and water in a methanol-based reagent. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 500-600 C and weighing the residual mass. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals (e.g., Pb, Cd, Hg) after acid digestion by measuring atomic absorption at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using an anion-exchange column and conductivity detection. |
| Related Substances | HPLC with UV Detection | Separates and quantifies impurities using reversed-phase chromatography and UV absorbance at 210-254 nm. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Measures weight loss upon heating to 105 C under controlled airflow to determine volatile content. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in a 1% w/v aqueous suspension using a calibrated pH electrode. |
| Sulfated Ash | Gravimetric Analysis | Measures non-volatile inorganic residue after incineration with sulfuric acid treatment and subsequent ignition. |
| Particle Size Distribution | Laser Diffraction | Determines particle size distribution by analyzing angular variation in laser light scattering from a dispersed sample. |
| Melting Point | Capillary Melting Point Apparatus | Identifies melting range by observing phase transition of a packed capillary sample under controlled heating. |
| Organic Volatile Impurities | Gas Chromatography (GC) with FID | Detects and quantifies residual solvents using capillary GC separation and flame ionization detection. |
Technical Specifications of 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-220 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE
Industrial 3-AMINO-1H-ISOINDOLE HYDROCHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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