(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 767340-03-4 |
| Product name | (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 767340-03-4
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 767340-03-4 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 767340-03-4
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type 2 diabetes | Used as a key intermediate in the synthesis of sitagliptin, introducing the trifluoromethyl-triazolopyrazine moiety via chemical synthesis and coupling it with a β-amino acid fragment to construct the active molecular scaffold |
Manufacturing Quality Control of 767340-03-4
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at specified wavelength. |
| Related Substances | HPLC-DAD or HPLC-MS | Separation and detection of structurally related impurities using gradient HPLC with diode-array or mass spectrometric detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents based on retention time and peak area relative to internal standard calibration. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generated electrochemically or added reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Catalysts (e.g., Pd, Ni) | ICP-OES | Elemental analysis of transition metal catalyst residues following microwave-assisted acid digestion and plasma emission detection. |
| Chiral Purity | Chiral HPLC | Enantioselective separation on chiral stationary phase with UV detection to assess enantiomeric excess. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry or wet dispersion based on angular scattering intensity of laser light. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, observed visually or automatically via optical detection. |
| Loss on Drying | Gravimetric Analysis (Thermogravimetry) | Mass loss measured after heating under controlled conditions to remove volatile components including moisture and solvents. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens using filtration, membrane transfer, and incubation on selective media. |
Technical Specifications of 767340-03-4
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Residue on Ignition | <=0.3% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 767340-03-4
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 767340-03-4
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Industrial 767340-03-4 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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