(+)-Camptothecin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7689-03-4 |
| Product name | (+)-Camptothecin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (+)-Camptothecin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (+)-Camptothecin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (+)-Camptothecin
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Anticancer drugs | Semi-synthetic camptothecin derivatives are used in the manufacture of anticancer agents, including irinotecan and topotecan. |
| Research | Biological research | Used as a DNA topoisomerase I inhibitor in cell biology and molecular biology experiments. |
| Pharmaceutical development | New drug development | Employed as a lead compound or reference standard in new drug discovery and development. |
Manufacturing Quality Control of (+)-Camptothecin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-DAD | Separates and detects structurally related impurities using gradient elution and diode-array detection for spectral confirmation. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Determines trace metal contaminants (Pb, Cd, As, Hg, Ni) via inductively coupled plasma mass spectrometry with isotopic quantification. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generated electrochemically in pyridine-free reagent. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after incineration at 700-800 C and weighing of residual residue. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by determining the angle of rotation of plane-polarized light at 20 C using sodium D-line (589 nm). |
| pH of Solution | Potentiometric pH Measurement | Determines acidity/basicity of a defined aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size by measuring angular variation in laser light scattering intensity. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (E. coli, Salmonella) using selective culture media. |
| Organic Volatile Impurities | GC-MS | Identifies and quantifies genotoxic impurities (e.g., chloromethane, epichlorohydrin) using gas chromatography coupled to mass spectrometry. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube and controlled heating rate. |
Technical Specifications of (+)-Camptothecin
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (HPLC) |
| Melting Point | 264-266°C |
| Optical Rotation | +37.0 to +42.0° (c=1, in methanol) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (+)-Camptothecin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (+)-Camptothecin
Packaging of (+)-Camptothecin
Industrial (+)-Camptothecin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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