China Factory Direct
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| CAS number | 76932-48-4 |
| Product name | (R)-N-Boc-1-Naphthylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral drug synthesis intermediate for constructing naphthyl-containing protease inhibitors or GPCR-targeting compounds | Used as a chiral building block in solid-phase peptide synthesis (SPPS) or solution-phase coupling reactions; after Boc deprotection, coupled with other amino acids or fragments via condensation |
| Organic Synthesis | Chiral ligand or catalyst precursor for asymmetric catalysis | Employed to prepare chiral phosphine ligands or N-heterocyclic carbene ligands, where the 3-(1-naphthyl) group provides steric bulk and π-electronic effects |
| Materials Science | Building block for functionalized chiral organic semiconductors or liquid crystal molecules | Incorporated into conjugated backbones via Suzuki or Ullmann coupling to modulate molecular chirality and optoelectronic properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220-254 nm, comparing peak area to a reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous pyridine/methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg) after acid digestion by inductively coupled plasma mass spectrometry with isotopic detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature (600-800 C) incineration and cooling in a desiccator. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determines pH of a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample using light scattering pattern to calculate size distribution by Mie theory. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of meniscus collapse. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtering solution through sterile membrane, placing on TSA agar, and counting CFUs after incubation. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +53.0 to +56.0 deg (c=1, in 1M HCl) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.