China Factory Direct
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| CAS number | 76985-09-6 |
| Product name | 3-(2-Naphthyl)-D-alanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates | Used in the synthesis of peptide-based or small-molecule chiral drugs, typically prepared via asymmetric synthesis or resolution methods |
| Chemicals | Organic synthesis raw material | Applied in fine chemical synthesis, involving coupling reactions, protecting group manipulations, and related processes |
| Research & Development | Drug discovery and screening | Employed in structure–activity relationship (SAR) studies, enzyme inhibitor development, and other assays, commonly using solid-phase or solution-phase synthesis techniques |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220–280 nm, comparing peak area against a certified reference standard. |
| Optical Rotation | [α]D | Measurement of specific rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm enantiomeric identity and purity. |
| Residual Solvents | GC-FID | Qualitative and quantitative analysis of volatile organic solvents (e.g., methanol, ethyl acetate, toluene) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Ultra-trace quantification of toxic elements (Pb, Cd, Hg, As, Ni) after acid digestion, based on elemental mass spectrometry detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric electrochemical reaction. |
| Related Substances (Impurities) | HPLC-UV/DAD | Separation and detection of structurally related impurities (e.g., starting materials, diastereomers, degradation products) using gradient HPLC with diode-array detection. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration (500–600 °C) followed by precise weighing of residual residue. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated pH electrode in a saturated or near-saturated aqueous suspension to assess acid-base behavior. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering principles to determine volumetric particle size distribution (D10, D50, D90). |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using controlled heating and visual observation of meniscus collapse. |
| Chloride Content | Ion Chromatography (IC) | Quantification of chloride anion after sample dissolution and filtration, using suppressed conductivity detection with anion-exchange column. |
| Specific Optical Rotation Purity | Chiral HPLC | Enantioselective separation on chiral stationary phase (e.g., cellulose-based) to quantify % enantiomeric excess (ee) relative to D-3-(2-naphthyl)alanine reference. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial compendia (USP <61>, <62>). |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Optical Rotation | +11.0 to +14.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.