China Factory Direct
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| CAS number | 769944-78-7 |
| Product name | 1-N-BOC-4-(4-BROMOPHENYL)PIPERIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serves as a synthetic intermediate for preparing piperidine-containing drug molecules, such as antipsychotics, analgesics, or targeted receptor modulators | Participates in coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to construct complex molecular frameworks following deprotection (e.g., Boc removal with TFA) |
| Organic Synthesis | Used as a key building block for constructing 4-aryl piperidine structural units, suitable for diversity-oriented synthesis | Undergoes cross-coupling with aryl boronic acids under palladium catalysis, or undergoes functional group transformations to introduce additional substituents |
| Medicinal Chemistry | Employed in the development of lead compound libraries for novel GPCR ligands or neurotransmitter transporter inhibitors | Serves as a core scaffold for structural optimization and structure–activity relationship (SAR) studies via N-alkylation or aryl modification |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV absorbance relative to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration with iodine-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metal elements by ionization in plasma and mass spectrometric detection. |
| Chloride Impurity | Ion Chromatography | Separates and detects chloride ions using anion-exchange column and conductivity detection. |
| Residual Palladium | ICP-MS | Specific quantification of palladium catalyst residue after acid digestion and plasma ionization. |
| Optical Rotation | [a]D Measurement | Determines specific rotation using sodium D-line light to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by weight loss after controlled heating under vacuum or nitrogen. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension to assess acidic/basic impurities. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.