4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 770-30-9 |
| Product name | 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for fungicides, used in the synthesis of strobilurin-class fungicides such as azoxystrobin | Used to prepare azoxystrobin via multi-step reactions including cyclization and oxidation with o-phenylenediamine or its derivatives |
| Pharmaceuticals | Intermediate for anticancer drugs, used in the synthesis of pyrimidine-based kinase inhibitors | Serves as a key heterocyclic scaffold in coupling or nucleophilic substitution reactions to construct active molecules targeting protein kinases |
Manufacturing Quality Control of 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, DMF) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Quantitative determination of trace metal contaminants (e.g., Pb, Cd, Ni, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppq sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against sodium chloride calibration standards. |
| Sulfate Impurity | Ion Chromatography | Anion-exchange chromatography with suppressed conductivity detection to measure sulfate content in sample solution. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after high-temperature ashing (700-800 C) of the sample in a platinum crucible. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated digital melting point instrument. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against defined reference standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry dispersion mode using Mie theory-based light scattering analysis. |
| Bulk Density | Tap Density Measurement | Determination of mass per unit volume after standardized mechanical tapping of a known mass in a graduated cylinder. |
Technical Specifications of 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 192-196°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
Safety Information of 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
Industrial 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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