4-Phenylpiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 771-99-3 |
| Product name | 4-Phenylpiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Phenylpiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Phenylpiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Phenylpiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key synthetic intermediate for opioid analgesics (e.g., pethidine) | Used in organic synthesis and catalytic hydrogenation |
| Pharmaceutical R&D | Reference standard for pharmacological studies of μ-opioid receptor agonists | Applied in biochemical assays and in vitro experiments |
| Organic Synthesis | Building block for constructing complex nitrogen-containing heterocyclic compounds | Used in nucleophilic substitution and reductive amination |
| Analytical Chemistry | Reference standard for chromatographic analysis | Applied in high-performance liquid chromatography (HPLC) analysis |
Manufacturing Quality Control of 4-Phenylpiperidine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white powder), and check for clumping or visible impurities. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with a reference standard spectrum to confirm consistency in functional groups and molecular structural characteristic peaks. |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR or ¹³C-NMR to analyze chemical shifts and coupling constants of hydrogen or carbon atoms, confirming the molecular structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilize reversed-phase columns (e.g., C18) with UV detection (typically at 210–254 nm), quantifying the main component using external standard or internal standard method. |
| Gas Chromatography (GC) | Applicable to samples with good volatility; identification by retention time and quantification by peak area, commonly used for high-purity sample analysis. | |
| Purity and Related Substances | HPLC Method | Employ gradient elution to separate the main peak from impurity peaks; calculate the area percentage of each impurity peak to assess purity and compliance with impurity limits. |
| GC Method | Detect volatile organic impurities and residual solvents; when coupled with mass spectrometry (GC-MS), unknown impurities can be further identified. | |
| Residual Solvents | Gas Chromatography (GC) | Test for residual solvents such as methanol, ethanol, acetone, dichloromethane, etc., used during manufacturing, according to pharmacopoeial requirements (e.g., Chinese Pharmacopoeia, USP). |
| Moisture Content | Karl Fischer Titration | Accurately determine water content in the sample; use volumetric method (suitable for higher moisture levels) or coulometric method (for trace moisture). |
| Melting Point | Melting Point Instrument Method | Determine the initial and final melting temperatures using an automatic or manual melting point apparatus, comparing results with reference values to assess purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | After sample digestion, measure concentrations of heavy metals such as lead, cadmium, mercury, and arsenic; ensure compliance with ICH or pharmacopoeial limits. |
| Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Enable highly sensitive detection of multiple trace metal impurities, suitable for quality control of high-purity active pharmaceutical ingredients. | |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | After high-temperature incineration and treatment with sulfuric acid, weigh the residue to assess total inorganic impurities. |
Technical Specifications of 4-Phenylpiperidine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Phenylpiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Phenylpiperidine
Packaging of 4-Phenylpiperidine
Industrial 4-Phenylpiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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