Cyclopropyl 4-fluorophenyl ketone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 772-31-6 |
| Product name | Cyclopropyl 4-fluorophenyl ketone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Cyclopropyl 4-fluorophenyl ketone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Cyclopropyl 4-fluorophenyl ketone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Cyclopropyl 4-fluorophenyl ketone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of the antidepressant vortioxetine | Prepared via Grignard or organolithium addition to cyclopropyl ketone derivatives, followed by fluorination; alternatively, the ketone moiety is constructed by Suzuki coupling with 4-fluorophenylboronic acid followed by oxidation |
| Pharmaceutical Intermediates | Used in the preparation of candidate selective 5-HT3 receptor antagonists | Modified through multi-step transformations including reductive amination and acylation to introduce piperazine or morpholine ring systems |
| Pesticide R&D | Potential structural scaffold for novel insecticidal molecules | Employed as a fluorinated cyclopropyl building block in heterocycle coupling and functional group transformations to optimize target activity and metabolic stability |
Manufacturing Quality Control of Cyclopropyl 4-fluorophenyl ketone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reverse-phase chromatography and UV absorbance at specified wavelength. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) with FID | Volatile organic solvents are vaporized in sealed vials and quantified by GC-FID using calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities using standardized sodium hydroxide solution with phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Sample is ignited at 700-800 C after sulfuric acid treatment; residue mass is measured as percentage of original sample. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals after wet digestion, using lead as the limiting metal and flame or graphite furnace AAS. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Separation and detection of chloride ions via conductivity detection (IC) or argentometric titration with silver nitrate. |
| Melting Point | Capillary Melting Point Determination | Thermal transition observed visually or automatically as the temperature range over which solid transforms to liquid. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compounds in solution at specified concentration and path length. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Analysis of scattered laser light intensity patterns to determine volume-based particle size distribution in suspension. |
Technical Specifications of Cyclopropyl 4-fluorophenyl ketone
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% |
| Melting Point | 78–82°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Cyclopropyl 4-fluorophenyl ketone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Cyclopropyl 4-fluorophenyl ketone
Safety Information of Cyclopropyl 4-fluorophenyl ketone
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of Cyclopropyl 4-fluorophenyl ketone
Industrial Cyclopropyl 4-fluorophenyl ketone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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