China Factory Direct
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| CAS number | 772-33-8 |
| Product name | 2-HYDROXY-5-NITROBENZYL BROMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate in drug synthesis | Processed via organic synthesis reactions, including nitration and bromination |
| Pesticide Industry | Synthesis of insecticides or herbicides | Used as a raw material for constructing pesticide molecular structures |
| Dye Industry | Intermediate in dye synthesis | Employed as a starting material in coupling or condensation reactions |
| Fragrance Industry | Synthesis of fragrance compounds | Applied in esterification or alkylation reactions to produce odor-active compounds |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Characteristics | Visual Inspection, Melting Point Determination | Observe the color of the sample (usually light yellow to brown crystals), crystal form, and presence of impurities; determine the melting point range (literature value approximately 105–110°C) to assess purity. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a C18 chromatographic column with methanol/water or acetonitrile/water as the mobile phase, and a UV detector (wavelength 254–280 nm) for quantification. Calculate the main component content using external standard method, which is precise and suitable for impurity control. |
| Impurity Analysis | HPLC-UV / HPLC-MS | Use gradient elution to separate potential impurities (such as unreacted raw materials, de-brominated products, oxidation by-products). Identify the structure via retention time comparison and mass spectrometry, meeting ICH Q3B requirements. |
| Bromine Content | Combustion Ion Chromatography (CIC) or Bomb Combustion + Ion Chromatography | After combustion in an oxygen bomb, absorb the sample into an alkaline solution to convert it into bromide ions. Determine Br⁻ concentration using ion chromatography to verify if the bromine atom content matches the theoretical value (theoretical Br% ≈ 38.5%). |
| Moisture Content | Karl Fischer Titration | Determine trace moisture using coulometric or volumetric methods. Control moisture content within ≤0.5% to avoid hydrolysis or stability issues during storage. |
| Solvent Residues | Gas Chromatography (GC) | Use headspace or direct injection with capillary columns such as DB-624 to detect residual solvents like ethanol, acetone, and ethyl acetate from the production process, complying with ICH Q3C standards. |
| UV-Visible Absorption Spectroscopy | UV-Vis Spectrophotometry | Prepare a solution in ethanol or methanol and measure characteristic absorption peaks in the 200–400 nm range (e.g., λmax ≈ 320–340 nm) for qualitative identification and concentration estimation. |
| Melting Point | Capillary Melting Point Method | Precisely determine the melting range and compare with a reference standard to judge crystalline purity. Deviation in melting point may indicate the presence of impurities. |
| Heavy Metal Detection | Atomic Absorption Spectrometry (AAS) or ICP-MS | Determine the content of heavy metals such as lead, cadmium, mercury, and arsenic after acid digestion to ensure compliance with pharmaceutical or reagent-grade standards (e.g., ≤10 ppm). |
| Chloride/Sulfate Impurities | Colorimetric Method (Chinese Pharmacopoeia Method) | Compare with standard sodium chloride or potassium sulfate solutions to control chloride and sulfate ion impurities, suitable for screening of inorganic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Beige to pale yellow crystalline powder |
| Purity | >=98.5% |
| Melting Point | 72-76°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.