5,7-Dichloro-8-hydroxyquinoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 773-76-2 |
| Product name | 5,7-Dichloro-8-hydroxyquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5,7-Dichloro-8-hydroxyquinoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5,7-Dichloro-8-hydroxyquinoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5,7-Dichloro-8-hydroxyquinoline
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for fungicides and acaricides | Used in the synthesis of novel quinoline-based agricultural fungicides (e.g., chloroquinoline compounds) via nucleophilic substitution or condensation reactions to introduce active functional groups |
| Pharmaceuticals | Intermediate for antimicrobial agents | Serves as a key intermediate in the synthesis of antimalarial and antimicrobial agents (e.g., hydroxyquinoline derivatives), participating in cyclization, halogenation, or metal coordination reactions |
| Materials | Metal chelating agent and corrosion inhibitor additive | Forms stable chelates with metal ions such as copper and zinc, inhibiting metal-catalyzed oxidative degradation in coatings, plastics, and lubricants |
| Analytical Chemistry | Colorimetric reagent and complexometric titration reagent for metal ions | Leverages its ability to form colored complexes with metal ions such as Fe³⁺, Al³⁺, and Cu²⁺ for colorimetric analysis or complexometric titration |
Manufacturing Quality Control of 5,7-Dichloro-8-hydroxyquinoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD or HPLC-MS | Separation and identification/quantification of impurities (e.g., mono-chloro isomers, quinoline derivatives) using gradient elution and spectral or mass confirmation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., toluene, ethanol, DMF) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, achieving sub-ppb sensitivity and compliance with ICH Q3D. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Measurement of mass loss upon heating at 105 °C under controlled conditions to determine volatile content including water and residual solvents. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration with silver nitrate using a silver indicator electrode to quantify total chloride ions released from C–Cl bond hydrolysis. |
| Melting Point | Capillary Melting Point Apparatus | Determination of sharpness and temperature range of solid–liquid transition, verifying crystalline identity and purity per USP <741>. |
| Residue on Ignition | Sulfated Ash Gravimetry | High-temperature incineration (600–800 °C) followed by gravimetric measurement of inorganic residue to assess inorganic impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values, critical for downstream formulation and dissolution behavior. |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical quantification of water via iodine generation and stoichiometric reaction, suitable for low-level moisture (<0.1%). |
Technical Specifications of 5,7-Dichloro-8-hydroxyquinoline
| Test Item | Specification |
|---|---|
| Appearance | Brown crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Solubility | Soluble in ethanol, chloroform; slightly soluble in water |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5,7-Dichloro-8-hydroxyquinoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5,7-Dichloro-8-hydroxyquinoline
Safety Information of 5,7-Dichloro-8-hydroxyquinoline
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5,7-Dichloro-8-hydroxyquinoline
Industrial 5,7-Dichloro-8-hydroxyquinoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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